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Literature DB >> 20593078

Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells.

Xin Li¹, Shijing Qian, Qiaojun He, Bo Yang, Jia Li, Yongzhou Hu.

Abstract

A new fluorescent turn-on probe for the rapid optical sensing of thiols has been designed and synthesized. The probe displays high on/off signal ratios and high selectivity towards thiols. The potential of the probe as a biosensor for thiols was demonstrated by imaging of thiols in living cells.

Entities: Chemical

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Year: 2010 PMID： 20593078 DOI： 10.1039/c004344c

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

8 in total

1. Conjugate addition/cyclization sequence enables selective and simultaneous fluorescence detection of cysteine and homocysteine.

Authors: Xiaofeng Yang; Yixing Guo; Robert M Strongin
Journal: Angew Chem Int Ed Engl Date: 2011-09-20 Impact factor: 15.336

2. The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?

Authors: Ji Cao; Meidan Ying; Nan Xie; Guanyu Lin; Rong Dong; Jun Zhang; Hailin Yan; Xiaochun Yang; Qiaojun He; Bo Yang
Journal: Antioxid Redox Signal Date: 2014-02-19 Impact factor: 8.401

3. Fluorescent Properties of BODIPY Sensors Based on Photoinduced Electron Transfer.

Authors: Yu S Marfin; M V Shipalova; V O Kurzin; K V Ksenofontova; A V Solomonov; E V Rumyantsev
Journal: J Fluoresc Date: 2016-08-16 Impact factor: 2.217

4. Stimuli-Responsive Polymer Film that Autonomously Translates a Molecular Detection Event into a Macroscopic Change in Its Optical Properties via a Continuous, Thiol-Mediated Self-Propagating Reaction.

Authors: Hemakesh Mohapatra; Hyungwoo Kim; Scott T Phillips
Journal: J Am Chem Soc Date: 2015-09-23 Impact factor: 15.419

Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells.

1. Conjugate addition/cyclization sequence enables selective and simultaneous fluorescence detection of cysteine and homocysteine.

2. The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?

3. Fluorescent Properties of BODIPY Sensors Based on Photoinduced Electron Transfer.

4. Stimuli-Responsive Polymer Film that Autonomously Translates a Molecular Detection Event into a Macroscopic Change in Its Optical Properties via a Continuous, Thiol-Mediated Self-Propagating Reaction.

5. A highly GSH-sensitive SN-38 prodrug with an "OFF-to-ON" fluorescence switch as a bifunctional anticancer agent.

6. Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution.

7. A Red-Emitting, Multidimensional Sensor for the Simultaneous Cellular Imaging of Biothiols and Phosphate Ions.

Review 8. Thiol reactive probes and chemosensors.