Literature DB >> 20592745

Target identification: HIF2alpha central player in osteoarthritis.

Alexandra Flemming.   

Abstract

Entities:  

Year:  2010        PMID： 20592745     DOI： 10.1038/nrd3210

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  2 in total

1.  Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction.

Authors:  Siyoung Yang; Jonghwan Kim; Je-Hwang Ryu; Hwanhee Oh; Churl-Hong Chun; Byoung Ju Kim; Byoung Hyun Min; Jang-Soo Chun
Journal:  Nat Med       Date:  2010-05-23       Impact factor: 53.440

2.  Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

Authors:  Taku Saito; Atsushi Fukai; Akihiko Mabuchi; Toshiyuki Ikeda; Fumiko Yano; Shinsuke Ohba; Nao Nishida; Toru Akune; Noriko Yoshimura; Takumi Nakagawa; Kozo Nakamura; Katsushi Tokunaga; Ung-Il Chung; Hiroshi Kawaguchi
Journal:  Nat Med       Date:  2010-05-23       Impact factor: 53.440
  2 in total
  3 in total

Review 1.  Biological aspects of early osteoarthritis.

Authors:  Henning Madry; Frank P Luyten; Andrea Facchini
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-10-19       Impact factor: 4.342

2.  Intra-articular delivery of anti-Hif-2α siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice.

Authors:  Y Pi; X Zhang; Z Shao; F Zhao; X Hu; Y Ao
Journal:  Gene Ther       Date:  2015-04-16       Impact factor: 5.250

3.  Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS.

Authors:  Janine Bleil; Joachim Sieper; Rene Maier; Uwe Schlichting; Axel Hempfing; Uta Syrbe; Heiner Appel
Journal:  Arthritis Res Ther       Date:  2015-07-17       Impact factor: 5.156
  3 in total

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