Literature DB >> 2059200

Protein kinase activity of rat brain hexokinase.

V Adams1, L D Griffin, B D Gelb, E R McCabe.   

Abstract

Hexokinase 1 (HK1) purified from rat brain exhibits protein kinase activity, including autophosphorylation and phosphorylation of histone H2A. This protein kinase activity is observed only in the absence of the HK1 carbohydrate substrate, glucose. Analysis of the ATP-binding domains of the mammalian HK1 protein sequences shows significant homology with other mammalian protein kinases.

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Year:  1991        PMID: 2059200     DOI: 10.1016/0006-291x(91)90652-n

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  12 in total

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