OBJECTIVE: The purpose of the study was to delineate how affective symptoms (AS) influence quality of life (QOL) for individuals with drug-refractory epilepsy (DRE) and those with well-controlled epilepsy (WCE) independently. METHODS: All subjects participating in the study were asked to complete reliable and validated self-report health questionnaires, including AS, measured with the Korean versions of the Beck Depression Inventory, Beck Anxiety Inventory, and Quality of Life in Epilepsy Inventory-31 (QOLIE-31). We examined predictors of QOLIE-31 scores among the various demographic and clinical factors. We compared the effects of AS on QOL between patients with DRE and those with WCE and investigated the differential effects of seizure control and AS on QOL. RESULTS: Two hundred forty-nine patients with DRE or WCE were included in the study. The strongest predictor of QOL was AS, followed by seizure control and MRI abnormality. Affective symptoms had almost two times the effect of seizure control and six times the effect of MRI abnormality. Poorest QOL was noted in patients with DRE with AS, followed by those with WCE with AS, DRE without AS, and WCE without AS. CONCLUSION: The major determinant of QOL in patients with epilepsy is AS rather than DRE or WCE status. Copyright 2010 Elsevier Inc. All rights reserved.
OBJECTIVE: The purpose of the study was to delineate how affective symptoms (AS) influence quality of life (QOL) for individuals with drug-refractory epilepsy (DRE) and those with well-controlled epilepsy (WCE) independently. METHODS: All subjects participating in the study were asked to complete reliable and validated self-report health questionnaires, including AS, measured with the Korean versions of the Beck Depression Inventory, Beck Anxiety Inventory, and Quality of Life in Epilepsy Inventory-31 (QOLIE-31). We examined predictors of QOLIE-31 scores among the various demographic and clinical factors. We compared the effects of AS on QOL between patients with DRE and those with WCE and investigated the differential effects of seizure control and AS on QOL. RESULTS: Two hundred forty-nine patients with DRE or WCE were included in the study. The strongest predictor of QOL was AS, followed by seizure control and MRI abnormality. Affective symptoms had almost two times the effect of seizure control and six times the effect of MRI abnormality. Poorest QOL was noted in patients with DRE with AS, followed by those with WCE with AS, DRE without AS, and WCE without AS. CONCLUSION: The major determinant of QOL in patients with epilepsy is AS rather than DRE or WCE status. Copyright 2010 Elsevier Inc. All rights reserved.
Authors: Christine B Baca; Barbara G Vickrey; Rochelle Caplan; Stefanie D Vassar; Anne T Berg Journal: Pediatrics Date: 2011-11-28 Impact factor: 7.124
Authors: Hamada Hamid; Karen Blackmon; Xiangyu Cong; James Dziura; Lauren Y Atlas; Barbara G Vickrey; Anne T Berg; Carl W Bazil; John T Langfitt; Thaddeus S Walczak; Michael R Sperling; Shlomo Shinnar; Orrin Devinsky Journal: Neurology Date: 2014-01-31 Impact factor: 9.910
Authors: Carlos R Camara-Lemarroy; Mariana Hoyos; Beatriz E Ibarra-Yruegas; Marco A Díaz-Torres; Rolando De León Journal: Neurol Sci Date: 2017-07-25 Impact factor: 3.307
Authors: Maurizio Pompili; Gianluca Serafini; Marco Innamorati; Franco Montebovi; Dorian A Lamis; Mariantonietta Milelli; Manuela Giuliani; Matteo Caporro; Paolo Tisei; David Lester; Mario Amore; Paolo Girardi; Carla Buttinelli Journal: World J Psychiatry Date: 2014-12-22