| Literature DB >> 20590136 |
Yang Yang1, Ke Zheng, Jiannan Zhao, Jian Shi, Lili Lin, Xiaohua Liu, Xiaoming Feng.
Abstract
The asymmetric direct vinylogous aldol reaction of unactivated gamma-butenolide with aldehydes has been developed, giving the corresponding 5-(1'-hydroxy)butenolide derivatives in high yields (up to 93%) and enantioselectivities (up to 83% ee) under mild conditions.Entities:
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Year: 2010 PMID： 20590136 DOI： 10.1021/jo100946d
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354