Literature DB >> 20590015

[Incidental thyroid carcinoma: a multicentric experience].

Angela Pezzolla1, Giovanni Docimo, Roberto Ruggiero, Massimo Monacelli, Roberto Cirocchi, Domenico Parmeggiani, Giovanni Conzo, Adelmo Gubitosi, Serafina Lattarulo, Anna Ciampolillo, Nicola Avenia, Ludovico Docimo, Nicola Palasciano.   

Abstract

BACKGROUND: In recent years it has seen an increase of incidental thyroid carcinomas (ICs), most of the ICs are any microcarcinoma (MC). The term refers to a CT, predominantly papillary, and smaller than or equal to 1 cm. The MC is characterized by a papillary heterogeneous clinical behavior ranging from small outbreak discovered accidentally after surgery than the cancer that manifests clinically with lymph node metastases in the neck or rarely systemic.
METHODS: From January 2007 to June 2009, 1507 patients for benign disease were subjected to surgery.
RESULTS: Histological examination confirmed the diagnosis of benignity in 1339 cases. In 168, however, we detected unexpected, incidental carcinoma (CI). In patients with CI receiving total surgery (TT), the next iteration we agree with the endocrinologist. In cases of lobectomia, was run TT and was heading endocrinology. Of the 168 patients with incidental CT, 147 had papillary carcinomas, 12 follicular carcinomas, 5 follicular variant papillary carcinomas, 2 oncocytic carcinomas, 1 uncertain malignancy.
CONCLUSION: In our study has highlighted the lack of data (medical history, ultrasound, scintigraphic), they may portend the presence of a tumor in the specimen CI. In all patients with CI, the surgical indication was given for symptomatic disease, for impairment of thyroid function, for failure to respond to medical therapy or unable to continue. The IC is almost always a microcarcinoma, predominantly papillary, and smaller than or equal to 1 cm, has little biological aggressiveness and is susceptible to metabolic radioiodine therapy. On the basis of these data we feel reasonably acceptable to a close follow-up endocrine surgery, particularly in patients with multinodular disease and stress the need for a multi-specialized team.

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Mesh:

Year:  2010        PMID: 20590015

Source DB:  PubMed          Journal:  Recenti Prog Med        ISSN: 0034-1193


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