Literature DB >> 20586654

Chlorhexidine use in the neonatal intensive care unit: results from a national survey.

Pranita D Tamma1, Susan W Aucott, Aaron M Milstone.   

Abstract

Infection prevention guidelines do not endorse chlorhexidine gluconate (CHG) use in neonates who are less than 2 months old. A survey of US neonatology program directors revealed that most neonatal intensive care units use CHG, often with some restrictions. Prospective studies are needed to further address concerns regarding the safety of CHG in patients in the neonatal intensive care unit.

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Year:  2010        PMID： 20586654      PMCID： PMC2900383          DOI： 10.1086/655017

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  10 in total

1.  Strategies to prevent central line-associated bloodstream infections in acute care hospitals.

Authors:  Jonas Marschall; Leonard A Mermel; David Classen; Kathleen M Arias; Kelly Podgorny; Deverick J Anderson; Helen Burstin; David P Calfee; Susan E Coffin; Erik R Dubberke; Victoria Fraser; Dale N Gerding; Frances A Griffin; Peter Gross; Keith S Kaye; Michael Klompas; Evelyn Lo; Lindsay Nicolle; David A Pegues; Trish M Perl; Sanjay Saint; Cassandra D Salgado; Robert A Weinstein; Robert Wise; Deborah S Yokoe
Journal:  Infect Control Hosp Epidemiol       Date:  2008-10       Impact factor: 3.254

2.  Impact of newborn skin-cleansing with chlorhexidine on neonatal mortality in southern Nepal: a community-based, cluster-randomized trial.

Authors:  James M Tielsch; Gary L Darmstadt; Luke C Mullany; Subarna K Khatry; Joanne Katz; Steven C LeClerq; Shardaram Shrestha; Ramesh Adhikari
Journal:  Pediatrics       Date:  2007-01-08       Impact factor: 7.124

3.  Hexachlorophene myelinopathy in premature infants.

Authors:  H Powell; O Swarner; L Gluck; P Lampert
Journal:  J Pediatr       Date:  1973-06       Impact factor: 4.406

4.  Increased skin permeability in preterm infants.

Authors:  R L Nachman; N B Esterly
Journal:  J Pediatr       Date:  1971-10       Impact factor: 4.406

5.  Absorption of chlorhexidine from the intact skin of newborn infants.

Authors:  J Cowen; S H Ellis; J McAinsh
Journal:  Arch Dis Child       Date:  1979-05       Impact factor: 3.791

6.  A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates.

Authors:  J S Garland; C P Alex; C D Mueller; D Otten; C Shivpuri; M C Harris; M Naples; J Pellegrini; R K Buck; T L McAuliffe; D A Goldmann; D G Maki
Journal:  Pediatrics       Date:  2001-06       Impact factor: 7.124

7.  Effect of chlorhexidine gluconate on the skin integrity at PICC line sites.

Authors:  M Visscher; M V deCastro; L Combs; L Perkins; J Winer; N Schwegman; C Burkhart; P Bondurant
Journal:  J Perinatol       Date:  2009-08-20       Impact factor: 2.521

8.  Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trial.

Authors:  Luke C Mullany; Gary L Darmstadt; Subarna K Khatry; Joanne Katz; Steven C LeClerq; Shardaram Shrestha; Ramesh Adhikari; James M Tielsch
Journal:  Lancet       Date:  2006-03-18       Impact factor: 79.321

Review 9.  Chlorhexidine: expanding the armamentarium for infection control and prevention.

Authors:  Aaron M Milstone; Catherine L Passaretti; Trish M Perl
Journal:  Clin Infect Dis       Date:  2008-01-15       Impact factor: 9.079

10.  Alcohol burns in the neonate.

Authors:  A M Watkins; E J Keogh
Journal:  J Paediatr Child Health       Date:  1992-08       Impact factor: 1.954
  10 in total
  17 in total

1.  Chlorhexidine inhibits L1 cell adhesion molecule-mediated neurite outgrowth in vitro.

Authors:  Aaron M Milstone; Penny Bamford; Susan W Aucott; Ningfeng Tang; Kimberly R White; Cynthia F Bearer
Journal:  Pediatr Res       Date:  2013-10-14       Impact factor: 3.756

2.  Neonatal blood cultures: survey of neonatologists' practices.

Authors:  Basavaraj Kerur; Agnes Salvador; Allan Arbeter; David L Schutzman
Journal:  World J Pediatr       Date:  2012-08-12       Impact factor: 2.764

3.  Trends in Chlorhexidine Use in US Neonatal Intensive Care Units: Results From a Follow-Up National Survey.

Authors:  Julia Johnson; Rebecca Bracken; Pranita D Tamma; Susan W Aucott; Cynthia Bearer; Aaron M Milstone
Journal:  Infect Control Hosp Epidemiol       Date:  2016-06-20       Impact factor: 3.254

4.  Infection prevention practices in neonatal intensive care units reporting to the national healthcare safety network.

Authors:  Susan N Hocevar; Fernanda C Lessa; Lauren Gallagher; Craig Conover; Rachel Gorwitz; Martha Iwamoto
Journal:  Infect Control Hosp Epidemiol       Date:  2014-07-25       Impact factor: 3.254

Review 5.  Antiseptic use in the neonatal intensive care unit - a dilemma in clinical practice: An evidence based review.

Authors:  Sundar Sathiyamurthy; Jayanta Banerjee; Sunit V Godambe
Journal:  World J Clin Pediatr       Date:  2016-05-08

6.  Decolonization to prevent Staphylococcus aureus transmission and infections in the neonatal intensive care unit.

Authors:  V O Popoola; A M Milstone
Journal:  J Perinatol       Date:  2014-07-10       Impact factor: 2.521

7.  Consistency between guidelines and reported practice for reducing the risk of catheter-related infection in British paediatric intensive care units.

Authors:  Katie Harron; Geethanjali Ramachandra; Quen Mok; Ruth Gilbert
Journal:  Intensive Care Med       Date:  2011-08-30       Impact factor: 17.440

8.  Methicillin-resistant Staphylococcus aureus colonization: a three-year prospective study in a neonatal intensive care unit in Italy.

Authors:  Daniela M Geraci; Mario Giuffrè; Celestino Bonura; Domenica Matranga; Aurora Aleo; Laura Saporito; Giovanni Corsello; Anders Rhod Larsen; Caterina Mammina
Journal:  PLoS One       Date:  2014-02-05       Impact factor: 3.240

9.  Impact of 1% chlorhexidine gluconate bathing and emollient application on bacterial pathogen colonization dynamics in hospitalized preterm neonates - A pilot clinical trial.

Authors:  Angela Dramowski; Sheylyn Pillay; Adrie Bekker; Ilhaam Abrahams; Mark F Cotton; Susan E Coffin; Andrew C Whitelaw
Journal:  EClinicalMedicine       Date:  2021-06-18

10.  Absorption and tolerability of aqueous chlorhexidine gluconate used for skin antisepsis prior to catheter insertion in preterm neonates.

Authors:  A K Chapman; S W Aucott; M M Gilmore; S Advani; W Clarke; A M Milstone
Journal:  J Perinatol       Date:  2013-05-23       Impact factor: 2.521
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