Literature DB >> 20584605

Ceratinadins A-C, new bromotyrosine alkaloids from an Okinawan marine sponge Pseudoceratina sp.

Yuji Kon1, Takaaki Kubota, Azusa Shibazaki, Tohru Gonoi, Jun'ichi Kobayashi.   

Abstract

Three new bromotyrosine alkaloids, ceratinadins A-C (1-3), were isolated from an Okinawan marine sponge Pseudoceratina sp. and the structures of 1-3 were elucidated on the basis of spectroscopic data. Ceratinadin A (1) was a novel bromotyrosine alkaloid possessing an N-imidazolyl-quinolinone moiety. Ceratinadins A (1) and B (2) showed antifungal activity. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20584605     DOI： 10.1016/j.bmcl.2010.06.015

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

Review 1.  Antifungal and antiviral products of marine organisms.

Authors:  Randy Chi Fai Cheung; Jack Ho Wong; Wen Liang Pan; Yau Sang Chan; Cui Ming Yin; Xiu Li Dan; He Xiang Wang; Evandro Fei Fang; Sze Kwan Lam; Patrick Hung Kui Ngai; Li Xin Xia; Fang Liu; Xiu Yun Ye; Guo Qing Zhang; Qing Hong Liu; Ou Sha; Peng Lin; Chan Ki; Adnan A Bekhit; Alaa El-Din Bekhit; David Chi Cheong Wan; Xiu Juan Ye; Jiang Xia; Tzi Bun Ng
Journal:  Appl Microbiol Biotechnol       Date:  2014-02-23       Impact factor: 4.813

2.  New antimicrobial bromotyrosine analogues from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis.

Authors:  Michael P Gotsbacher; Peter Karuso
Journal:  Mar Drugs       Date:  2015-03-16       Impact factor: 5.118

Review 3.  A Decade of Antifungal Leads from Natural Products: 2010-2019.

Authors:  Mohammed Aldholmi; Pascal Marchand; Isabelle Ourliac-Garnier; Patrice Le Pape; A Ganesan
Journal:  Pharmaceuticals (Basel)       Date:  2019-12-12

4.  Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway.

Authors:  Jui-Hsin Su; Yu-Cheng Chen; Mohamed El-Shazly; Ying-Chi Du; Chiang-Wen Su; Chia-Wei Tsao; Li-Lian Liu; Yalan Chou; Wen-Been Chang; Yin-Di Su; Michael Y Chiang; Yao-Tsung Yeh; Mei-Chin Lu
Journal:  Mar Drugs       Date:  2013-08-26       Impact factor: 5.118
  4 in total

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