Literature DB >> 20584563

A bioactive labdane diterpenoid from Curcuma amada and its semisynthetic analogues as antitubercular agents.

Sailendra Singh1, Jonnala Kotesh Kumar, Dharmendra Saikia, Karuna Shanker, Jay Prakash Thakur, Arvind Singh Negi, Suchitra Banerjee.   

Abstract

A labdane diterpene dialdehyde was first time isolated from the chloroform extract of rhizomes of Curcuma amada. This compound exhibited antitubercular activity (MIC=500 microg/mL) against Mycobacterium tuberculosis H(37)Rv strain in BACTEC-460 assay. Two of its semisynthetic analogues also exhibited antitubercular activity at 250-500 microg/mL. It is the first report on isolation and antimycobacterial activity of this dialdehyde from C. amada. 2010 Elsevier Masson SAS. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20584563     DOI： 10.1016/j.ejmech.2010.06.006

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  8 in total

1.  Bioactive Compounds from Medicinal Plants in Myanmar.

Authors:  Nwet Nwet Win; Hiroyuki Morita
Journal:  Prog Chem Org Nat Prod       Date:  2021

2.  Mango ginger (Curcuma amada Roxb.)--a promising spice for phytochemicals and biological activities.

Authors:  R S Policegoudra; S M Aradhya; L Singh
Journal:  J Biosci       Date:  2011-09       Impact factor: 1.826

3.  Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors.

Authors:  Renjitha Jalaja; Shyni G Leela; Praveen K Valmiki; Chettiyan Thodi F Salfeena; Kizhakkan T Ashitha; Venkata Rao D Krishna Rao; Mangalam S Nair; Raghu K Gopalan; Sasidhar B Somappa
Journal:  ACS Med Chem Lett       Date:  2018-06-18       Impact factor: 4.345

4.  In vitro antituberculosis activity of diterpenoids from the Vietnamese medicinal plant Croton tonkinensis.

Authors:  Woong Sik Jang; Md Anirban Jyoti; Sukyung Kim; Kung-Woo Nam; Thi Kim Quy Ha; Won Keun Oh; Ho-Yeon Song
Journal:  J Nat Med       Date:  2015-09-19       Impact factor: 2.343

5.  Isolation, structure determination, and antiaging effects of 2,3-pentanediol from endophytic fungus of Curcuma amada and docking studies.

Authors:  Sudeep Tiwari; Sailendra Singh; Pallavi Pandey; Shilpi K Saikia; Arvind Singh Negi; Shailendra K Gupta; Rakesh Pandey; Suchitra Banerjee
Journal:  Protoplasma       Date:  2014-02-11       Impact factor: 3.356

6.  Experimental and modeling studies on microwave-assisted extraction of mangiferin from Curcuma amada.

Authors:  Jeke Kullu; Abhishek Dutta; Denis Constales; Surabhi Chaudhuri; Debjani Dutta
Journal:  3 Biotech       Date:  2013-04-21       Impact factor: 2.406

7.  Proteomic Insights on the Metabolism of Penicillium janczewskii during the Biotransformation of the Plant Terpenoid Labdanolic Acid.

Authors:  Isabel Martins; Adélia Varela; Luís M T Frija; Mónica A S Estevão; Sébastien Planchon; Jenny Renaut; Carlos A M Afonso; Cristina Silva Pereira
Journal:  Front Bioeng Biotechnol       Date:  2017-07-31

8.  α-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives.

Authors:  Yuri Yoshioka; Naori Yoshimura; Shinichi Matsumura; Hiroto Wada; Maya Hoshino; Shouhei Makino; Masanori Morimoto
Journal:  Molecules       Date:  2019-11-10       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.