Literature DB >> 20583920

Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants.

Shabir A Madhi1, Peter Adrian, Mark F Cotton, James A McIntyre, Patrick Jean-Philippe, Shawn Meadows, Sharon Nachman, Helena Käyhty, Keith P Klugman, Avye Violari.   

Abstract

Serotype-specific antibody concentration and opsonophagocytic activity (OPA) were evaluated after 3 doses of pneumococcal conjugate vaccine. Groups included human immunodeficiency virus (HIV)-positive infants with CD4(+) cell percentages > or =25% who initiated immediate antiretroviral treatment (the HIV+/ART+ group) or whose antiretroviral treatment was deferred until clinically or immunologically indicated (the HIV+/ART- group). Immune responses were also evaluated in HIV-noninfected infants born to HIV-seronegative (M-/I-) or HIV-positive mothers (M+/I-). Antibody concentrations were similar between HIV+/ART+ and HIV+/ART- infants. However, antibody concentrations were lower in M-/I- infants than in M+/I- infants. Nevertheless, M-/I- infants had superior OPA responses, compared with those in HIV+/ART+ infants, who in turn had better OPA responses, compared with those in HIV+/ART- infants.

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Year:  2010        PMID： 20583920      PMCID： PMC2902789          DOI： 10.1086/653704

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  14 in total

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Authors: 
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Authors:  Ron Dagan; Noga Givon-Lavi; David Greenberg; Bernard Fritzell; Claire-Anne Siegrist
Journal:  J Infect Dis       Date:  2010-05-15       Impact factor: 5.226

5.  Safety and immunogenicity of three doses of a five-valent pneumococcal conjugate vaccine in children younger than two years with and without human immunodeficiency virus infection.

Authors:  J C King; P E Vink; J J Farley; M Smilie; M Parks; R Lichenstein
Journal:  Pediatrics       Date:  1997-04       Impact factor: 7.124

6.  Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children.

Authors:  Shabir A Madhi; Locadiah Kuwanda; Clare Cutland; Anne Holm; Helena Käyhty; Keith P Klugman
Journal:  Pediatr Infect Dis J       Date:  2005-05       Impact factor: 2.129

7.  Safety and immunogenicity of a heptavalent pneumococcal conjugate vaccine in infants with human immunodeficiency virus type 1 infection.

Authors:  Sharon Nachman; Soyeon Kim; James King; Elaine J Abrams; David Margolis; Ann Petru; William Shearer; Elizabeth Smith; Jack Moye; Suzette Blanchard; Elizabeth Hawkins; Pamela Bouquin; Peter Vink; Mindy Benson; Scharla Estep; Frank Malinoski
Journal:  Pediatrics       Date:  2003-07       Impact factor: 7.124

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10.  Gamma interferon production in response to Mycobacterium bovis BCG and Mycobacterium tuberculosis antigens in infants born to human immunodeficiency virus-infected mothers.

Authors:  Annelies Van Rie; Shabir A Madhi; Jayvant R Heera; Stephen Meddows-Taylor; Aaron M Wendelboe; Fiona Anthony; Avy Violari; Caroline T Tiemessen
Journal:  Clin Vaccine Immunol       Date:  2006-02
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  48 in total

Review 1.  The potential impact of pneumococcal conjugate vaccine in Africa: Considerations and early lessons learned from the South African experience.

Authors:  Shabir A Madhi; Marta C Nunes
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2.  Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: optimizing health in preparation for adult life.

Authors:  A Bamford; A Turkova; H Lyall; C Foster; N Klein; D Bastiaans; D Burger; S Bernadi; K Butler; E Chiappini; P Clayden; M Della Negra; V Giacomet; C Giaquinto; D Gibb; L Galli; M Hainaut; M Koros; L Marques; E Nastouli; T Niehues; A Noguera-Julian; P Rojo; C Rudin; H J Scherpbier; G Tudor-Williams; S B Welch
Journal:  HIV Med       Date:  2015-02-03       Impact factor: 3.180

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Journal:  Clin Infect Dis       Date:  2015-06-09       Impact factor: 9.079

4.  Immunogenicity and safety of 1 vs 2 doses of quadrivalent meningococcal conjugate vaccine in youth infected with human immunodeficiency virus.

Authors:  Jorge Lujan-Zilbermann; Meredith G Warshaw; Paige L Williams; Stephen A Spector; Michael D Decker; Mark J Abzug; Barb Heckman; Adam Manzella; Bill Kabat; Patrick Jean-Philippe; Sharon Nachman; George K Siberry
Journal:  J Pediatr       Date:  2012-05-22       Impact factor: 4.406

5.  Favourable outcome in a child with symptomatic diagnosis of Glutaric aciduria type 1 despite vertical HIV infection and minor head trauma.

Authors:  Angeline Thomas; Els F M Dobbels; Priscilla E Springer; Christelle Ackermann; Mark F Cotton; Barbara Laughton
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6.  Longitudinal study on Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonization in HIV-infected and -uninfected infants vaccinated with pneumococcal conjugate vaccine.

Authors:  Shabir A Madhi; Alane Izu; Marta C Nunes; Avye Violari; Mark F Cotton; Patrick Jean-Philippe; Keith P Klugman; Anne von Gottberg; Nadia van Niekerk; Peter V Adrian
Journal:  Vaccine       Date:  2015-04-21       Impact factor: 3.641

7.  Safety and immunogenicity of a live attenuated pentavalent rotavirus vaccine in HIV-exposed infants with or without HIV infection in Africa.

Authors:  Myron J Levin; Jane C Lindsey; Susan S Kaplan; Werner Schimana; Jody Lawrence; Monica M McNeal; Mutsa Bwakura-Dangarembizi; Anthony Ogwu; Evans M Mpabalwani; Paul Sato; George Siberry; Margaret Nelson; Darcy Hille; Geoffrey A Weinberg; Adriana Weinberg
Journal:  AIDS       Date:  2017-01-02       Impact factor: 4.177

8.  Immunogenicity following the first and second doses of 7-valent pneumococcal conjugate vaccine in HIV-infected and -uninfected infants.

Authors:  Shabir A Madhi; Alane Izu; Avye Violari; Mark F Cotton; Ravindre Panchia; Els Dobbels; Poonam Sewraj; Nadia van Niekerk; Patrick Jean-Philippe; Peter V Adrian
Journal:  Vaccine       Date:  2012-12-08       Impact factor: 3.641

9.  HIV-associated CD4+/CD8+ depletion in infancy is associated with neurometabolic reductions in the basal ganglia at age 5 years despite early antiretroviral therapy.

Authors:  Kenneth K Mbugua; Martha J Holmes; Mark F Cotton; Eva-Maria Ratai; Francesca Little; Aaron T Hess; Els Dobbels; Andre J W Van der Kouwe; Barbara Laughton; Ernesta M Meintjes
Journal:  AIDS       Date:  2016-06-01       Impact factor: 4.177

10.  Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years.

Authors:  Jadrana T F Toich; Paul A Taylor; Martha J Holmes; Suril Gohel; Mark F Cotton; Els Dobbels; Barbara Laughton; Francesca Little; Andre J W van der Kouwe; Bharat Biswal; Ernesta M Meintjes
Journal:  Front Hum Neurosci       Date:  2018-01-11       Impact factor: 3.169
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