Literature DB >> 20580116

In the swim of things: recent insights to neurogenetic disorders from zebrafish.

Edor Kabashi1, Nathalie Champagne, Edna Brustein, Pierre Drapeau.   

Abstract

The advantage of zebrafish as a model to study human pathologies lies in the ease of manipulating gene expression in vivo. Here we focus on recent progress in our understanding of motor neuron diseases and neurodevelopmental disorders and discuss how novel technologies will permit further disease models to be developed. Together these advances set the stage for this simple functional model, with particular advantages for transgenesis, multigenic analyses and chemical biology, to become uniquely suited for advancing the functional genomics of neurological and possibly psychiatric diseases - from understanding the genetics and cell biology of degenerative and developmental disorders to the discovery of therapeutics. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20580116     DOI： 10.1016/j.tig.2010.05.004

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  21 in total

1.  Long-term proline exposure alters nucleotide catabolism and ectonucleotidase gene expression in zebrafish brain.

Authors:  Luiz Eduardo Baggio Savio; Fernanda Cenci Vuaden; Denis B Rosemberg; Maurício R Bogo; Carla Denise Bonan; Angela T S Wyse
Journal:  Metab Brain Dis       Date:  2012-06-07       Impact factor: 3.584

2.  ALS-linked protein disulfide isomerase variants cause motor dysfunction.

Authors:  Ute Woehlbier; Alicia Colombo; Mirva J Saaranen; Viviana Pérez; Jorge Ojeda; Fernando J Bustos; Catherine I Andreu; Mauricio Torres; Vicente Valenzuela; Danilo B Medinas; Pablo Rozas; Rene L Vidal; Rodrigo Lopez-Gonzalez; Johnny Salameh; Sara Fernandez-Collemann; Natalia Muñoz; Soledad Matus; Ricardo Armisen; Alfredo Sagredo; Karina Palma; Thergiory Irrazabal; Sandra Almeida; Paloma Gonzalez-Perez; Mario Campero; Fen-Biao Gao; Pablo Henny; Brigitte van Zundert; Lloyd W Ruddock; Miguel L Concha; Juan P Henriquez; Robert H Brown; Claudio Hetz
Journal:  EMBO J       Date:  2016-02-11       Impact factor: 11.598

3.  A novel approach to study motor neurons from zebrafish embryos and larvae in culture.

Authors:  Stacey A Sakowski; J Simon Lunn; Angela S Busta; Madeline Palmer; James J Dowling; Eva L Feldman
Journal:  J Neurosci Methods       Date:  2012-01-20       Impact factor: 2.390

4.  Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish.

Authors:  Fadi A Issa; Christopher Mazzochi; Allan F Mock; Diane M Papazian
Journal:  J Neurosci       Date:  2011-05-04       Impact factor: 6.167

5.  Localization of BDNF expression in the developing brain of zebrafish.

Authors:  E De Felice; I Porreca; E Alleva; P De Girolamo; C Ambrosino; E Ciriaco; A Germanà; P Sordino
Journal:  J Anat       Date:  2014-03-04       Impact factor: 2.610

Review 6.  Using C. elegans to decipher the cellular and molecular mechanisms underlying neurodevelopmental disorders.

Authors:  Carlos Bessa; Patrícia Maciel; Ana João Rodrigues
Journal:  Mol Neurobiol       Date:  2013-03-14       Impact factor: 5.590

7.  In vivo imaging of disease-related mitochondrial dynamics in a vertebrate model system.

Authors:  Gabriela Plucińska; Dominik Paquet; Alexander Hruscha; Leanne Godinho; Christian Haass; Bettina Schmid; Thomas Misgeld
Journal:  J Neurosci       Date:  2012-11-14       Impact factor: 6.167

Review 8.  The zebrafish as a model for complex tissue regeneration.

Authors:  Matthew Gemberling; Travis J Bailey; David R Hyde; Kenneth D Poss
Journal:  Trends Genet       Date:  2013-08-06       Impact factor: 11.639

9.  Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism.

Authors:  M Pilorge; C Fassier; H Le Corronc; A Potey; J Bai; S De Gois; E Delaby; B Assouline; V Guinchat; F Devillard; R Delorme; G Nygren; M Råstam; J C Meier; S Otani; H Cheval; V M James; M Topf; T N Dear; C Gillberg; M Leboyer; B Giros; S Gautron; J Hazan; R J Harvey; P Legendre; C Betancur
Journal:  Mol Psychiatry       Date:  2015-09-15       Impact factor: 15.992

Review 10.  Neuromuscular disorders in zebrafish: state of the art and future perspectives.

Authors:  Andrea Pappalardo; Letizia Pitto; Chiara Fiorillo; M Alice Donati; Claudio Bruno; Filippo M Santorelli
Journal:  Neuromolecular Med       Date:  2013-04-13       Impact factor: 3.843
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