Literature DB >> 205795

Membrane leakiness after viral infection and a new approach to the development of antiviral agents.

L Carrasco.   

Abstract

Viral development induces changes in the permeability properties of the plasma membrane of the host cell. Here it is shown that, because of this leakiness, inhibitors of protein synthesis normally impermeable to uninfected cells are able to enter infected cells and thereby specifically inhibit viral protein synthesis.

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Year:  1978        PMID： 205795     DOI： 10.1038/272694a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  47 in total

1.  Ion channels in icosahedral virus: a comparative analysis of the structures and binding sites at their fivefold axes.

Authors:  S G Kalko; R E Cachau; A M Silva
Journal:  Biophys J       Date:  1992-10       Impact factor: 4.033

2.  Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication.

Authors:  F J van Kuppeveld; J M Galama; J Zoll; P J van den Hurk; W J Melchers
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

3.  Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity.

Authors:  A Barco; L Carrasco
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

4.  NMR parameters of local anesthetics as biological markers of the cell-virus interactions.

Authors:  P E Valensin; M L Bianchi-Bandinelli; M L di Cairano; E Gaggelli; G Valensin
Journal:  Arch Virol       Date:  1985       Impact factor: 2.574

5.  Extraction and fingerprint analysis of simian virus 40 large and small T-antigens.

Authors:  A E Smith; R Smith; E Paucha
Journal:  J Virol       Date:  1978-10       Impact factor: 5.103

6.  The inhibition of nucleic acid synthesis in encephalomyocarditis virus-infected L929 cells: effects on nucleoside transport.

Authors:  J L Castrillo; L Carrasco
Journal:  Mol Cell Biochem       Date:  1986-06       Impact factor: 3.396

7.  Suppression of injuries caused by a lytic RNA virus (mengovirus) and their uncoupling from viral reproduction by mutual cell/virus disarmament.

Authors:  Olga V Mikitas; Yuri Y Ivin; Sergey A Golyshev; Natalia V Povarova; Svetlana I Galkina; Olga Y Pletjushkina; Elena S Nadezhdina; Anatoly P Gmyl; Vadim I Agol
Journal:  J Virol       Date:  2012-03-21       Impact factor: 5.103

8.  Mitochondrial calcium uptake during infection of chicken embryo cells with Semliki Forest virus.

Authors:  E Peterhans; E Haenggeli; P Wild; R Wyler
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

9.  Long-term biochemical changes in the islets of Langerhans in mice following infection with encephalomyocarditis virus.

Authors:  L N Hellqvist; C J Rhodes; K W Taylor
Journal:  Diabetologia       Date:  1984-05       Impact factor: 10.122

10.  Survey of virally mediated permeability changes.

Authors:  K A Foster; K Gill; K J Micklem; C A Pasternak
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857
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