Literature DB >> 20578706

Non-isoflavone phytochemicals in soy and their health effects.

Jie Kang1, Thomas M Badger, Martin J J Ronis, Xianli Wu.   

Abstract

Epidemiological and clinical studies have linked consumption of soy foods with low incidences of a number of chronic diseases, such as cardiovascular diseases, cancer, and osteoporosis. Over the past decades, enormous research efforts have been made to identify bioactive components in soy. Isoflavones and soy protein have been suggested as the major bioactive components in soy and have received considerable attention. However, there are hundreds of phytochemical components in soybeans and soy-based foods. In recent years, accumulating evidence has suggested that the isoflavones or soy proteins stripped of phytochemicals only reflect certain aspects of health effects associated with soy consumption. Other phytochemicals, either alone or in combination with isoflavones or soy protein, may be involved in the health effects of soy. This review attempts to summarize major non-isoflavone phytochemicals in soy, as well as their bioavailability and health effects. In addition, a brief discussion of components formed during food processing is also included.

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Year:  2010        PMID: 20578706     DOI: 10.1021/jf100901b

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN: 0021-8561            Impact factor:   5.279


  22 in total

1.  Long-term soy isoflavone supplementation and cognition in women: a randomized, controlled trial.

Authors:  V W Henderson; J A St John; H N Hodis; N Kono; C A McCleary; A A Franke; W J Mack
Journal:  Neurology       Date:  2012-06-05       Impact factor: 9.910

2.  Comparison between the impact of fermented and unfermented soy intake on the risk of liver cancer: the JPHC Study.

Authors:  Sarah Krull Abe; Norie Sawada; Junko Ishihara; Ribeka Takachi; Nagisa Mori; Taiki Yamaji; Taichi Shimazu; Atsushi Goto; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane
Journal:  Eur J Nutr       Date:  2020-07-27       Impact factor: 5.614

3.  Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents.

Authors:  Luísa Camacho; Sherry M Lewis; Michelle M Vanlandingham; Beth E Juliar; Greg R Olson; Ralph E Patton; Gonçalo Gamboa da Costa; Kellie Woodling; Estatira Sepehr; Matthew S Bryant; Daniel R Doerge; Mallikarjuna S Basavarajappa; Robert P Felton; K Barry Delclos
Journal:  Food Chem Toxicol       Date:  2016-05-24       Impact factor: 6.023

Review 4.  Determinants of food allergy.

Authors:  Madhan Masilamani; Scott Commins; Wayne Shreffler
Journal:  Immunol Allergy Clin North Am       Date:  2012-02       Impact factor: 3.479

5.  Anti-anxiety, cognitive, and steroid biosynthetic effects of an isoflavone-based dietary supplement are gonad and sex-dependent in rats.

Authors:  Jonathan Friedman; Cheryl Frye
Journal:  Brain Res       Date:  2010-12-15       Impact factor: 3.252

6.  Dietary soyasaponin attenuates 2,4-dinitrofluorobenzene-induced contact hypersensitivity via gut microbiota in mice.

Authors:  T Nagano; M Katase; K Tsumura
Journal:  Clin Exp Immunol       Date:  2018-10-07       Impact factor: 4.330

Review 7.  Regulation of the immune response by soybean isoflavones.

Authors:  Madhan Masilamani; John Wei; Hugh A Sampson
Journal:  Immunol Res       Date:  2012-12       Impact factor: 2.829

Review 8.  Effects of soy containing diet and isoflavones on cytochrome P450 enzyme expression and activity.

Authors:  Martin J J Ronis
Journal:  Drug Metab Rev       Date:  2016-07-20       Impact factor: 4.518

9.  Long-term soy consumption and tumor tissue MicroRNA and gene expression in triple-negative breast cancer.

Authors:  Xingyi Guo; Qiuyin Cai; Pingping Bao; Jie Wu; Wanqing Wen; Fei Ye; Wei Zheng; Ying Zheng; Xiao-Ou Shu
Journal:  Cancer       Date:  2016-05-16       Impact factor: 6.860

10.  Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells.

Authors:  Xiaolong Wang; Wenwen Qi; Yaming Li; Ning Zhang; Lun Dong; Mingjuan Sun; Jinjing Cun; Yan Zhang; Shangge Lv; Qifeng Yang
Journal:  PLoS One       Date:  2015-07-02       Impact factor: 3.240

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