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Literature DB >> 20578544

Delayed progression and inefficient transmission of HIV-2.

Bineeta Kashyap¹, Hitender Gautam, Sanjim Chadha, Preena Bhalla.

Abstract

We report a case of HIV-2 infection with delayed progression, taking approximately one and a half decades to develop HIV related symptoms. The spouse was still negative for HIV with a history of having regular unprotected sex with the index case which highlights the inefficient transmissibility of HIV-2. Continued surveillance is needed in screening of HIV-2 infection, especially in cases with a high index of suspicion and risk factors for HIV-2, as these patients develop AIDS related symptoms quite late due to delayed progression.

Entities: Disease Species

Mesh：

Year: 2010 PMID： 20578544

Source DB: PubMed Journal: Southeast Asian J Trop Med Public Health ISSN： 0125-1562 Impact factor: 0.267

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Cited

4 in total

1. The difference between HIV and syphilis prevalence and incidence cases: results from a cohort study in Nanjing, China, 2008-2010.

Authors: Weiming Tang; Giridhara R Babu; Jianjun Li; Ye Zhang; Gengfeng Fu; Xiping Huan; Joseph D Tucker; Jinkou Zhao; Roger Detels
Journal: Int J STD AIDS Date: 2014-09-23 Impact factor: 1.359

Delayed progression and inefficient transmission of HIV-2.

1. The difference between HIV and syphilis prevalence and incidence cases: results from a cohort study in Nanjing, China, 2008-2010.

2. Cyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates.

3. High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences.

4. HIV risk-reduction counseling and testing on behavior change of MSM.