Literature DB >> 20578035

Analyzing binding data.

Harvey J Motulsky1, Richard R Neubig.   

Abstract

Measuring the rate and extent of radioligand binding provides information on the number of binding sites, and their affinity and accessibility of these binding sites for various drugs. This unit explains how to design and analyze such experiments.

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Year:  2010        PMID： 20578035     DOI： 10.1002/0471142301.ns0705s52

Source DB:  PubMed          Journal:  Curr Protoc Neurosci        ISSN： 1934-8576


  10 in total

1.  Time-resolved fluorescence ligand binding for G protein-coupled receptors.

Authors:  Alexander Emami-Nemini; Thomas Roux; Marion Leblay; Emmanuel Bourrier; Laurent Lamarque; Eric Trinquet; Martin J Lohse
Journal:  Nat Protoc       Date:  2013-06-13       Impact factor: 13.491

2.  Dendrimer-mediated multivalent binding for the enhanced capture of tumor cells.

Authors:  Ja Hye Myung; Khyati A Gajjar; Jelena Saric; David T Eddington; Seungpyo Hong
Journal:  Angew Chem Int Ed Engl       Date:  2011-10-19       Impact factor: 15.336

3.  The TRPV1 channel in rodents is a major target for antinociceptive effect of the probiotic Lactobacillus reuteri DSM 17938.

Authors:  Azucena Perez-Burgos; Lu Wang; Karen-Anne McVey Neufeld; Yu-Kang Mao; Mustafa Ahmadzai; Luke J Janssen; Andrew M Stanisz; John Bienenstock; Wolfgang A Kunze
Journal:  J Physiol       Date:  2015-07-20       Impact factor: 5.182

4.  Aptamer-antibody hybrid ELONA that uses hybridization chain reaction to detect a urinary biomarker EN2 for bladder and prostate cancer.

Authors:  Eunseon Kim; Minji Kang; Changill Ban
Journal:  Sci Rep       Date:  2022-07-07       Impact factor: 4.996

5.  Fluorescence spectroscopic and calorimetry based approaches to characterize the mode of interaction of small molecules with DNA.

Authors:  Amrita Banerjee; Jasdeep Singh; Dipak Dasgupta
Journal:  J Fluoresc       Date:  2013-03-15       Impact factor: 2.217

6.  A D-amino acid containing peptide as a potent, noncovalent inhibitor of α5β1 integrin in human prostate cancer invasion and lung colonization.

Authors:  Donna M Veine; Hongren Yao; Daniel R Stafford; Kevin S Fay; Donna L Livant
Journal:  Clin Exp Metastasis       Date:  2014-01-25       Impact factor: 5.150

7.  Homocysteine-Thiolactone Modulates Gating of Mitochondrial Voltage-Dependent Anion Channel (VDAC) and Protects It from Induced Oxidative Stress.

Authors:  T Daniel Tuikhang Koren; Subhendu Ghosh
Journal:  J Membr Biol       Date:  2022-02-01       Impact factor: 1.843

8.  dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35.

Authors:  Luca Zinzula; Francesca Esposito; Daniela Pala; Enzo Tramontano
Journal:  Antiviral Res       Date:  2012-01-25       Impact factor: 5.970

9.  Cancer-Related Somatic Mutations in Transmembrane Helices Alter Adenosine A1 Receptor Pharmacology.

Authors:  Xuesong Wang; Willem Jespers; Kim A N Wolff; Jill Buytelaar; Adriaan P IJzerman; Gerard J P van Westen; Laura H Heitman
Journal:  Molecules       Date:  2022-06-10       Impact factor: 4.927

Review 10.  Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing.

Authors:  Stephane Demine; Michael L Schulte; Paul R Territo; Decio L Eizirik
Journal:  Int J Mol Sci       Date:  2020-10-01       Impact factor: 5.923
  10 in total

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