Literature DB >> 20576386

Solid non-invasive ovarian masses on MR: histopathology and a diagnostic approach.

Yumiko O Tanaka1, Satoshi Okada, Toyomi Satoh, Koji Matsumoto, Tsukasa Saida, Akinori Oki, Hiroyuki Yoshikawa, Manabu Minami.   

Abstract

PURPOSE: The purpose is to clarify the histopathology of the solid, non-invasive ovarian masses and to investigate the MR characteristics that distinguish benign from malignant.
MATERIALS AND METHODS: From 1996 to 2008, we identified 38 cases with predominantly solid non-invasive ovarian masses examined by contrast MR. We evaluated the signal intensity on T2WI and degree of contrast enhancement. In 31 of these cases with dynamic contrast study, we classified the enhancing patterns of the masses into gradually increasing and plateau after rapid increase patterns. RESULT: Sixteen cases were benign sex-cord stromal tumors, three were other types of benign tumors, nine cases were diagnosed with primary malignant ovarian tumors, and 10 showed metastatic tumors. Low intensity on T2WI was observed in 15 benign and 2 malignant tumors. The gradually increasing pattern was observed in all 17 benignancies and 5 of the 14 malignancies. In the equilibrium phase, the masses were weakly enhanced in all 19 benignancies and only 4 of 19 malignancies. The diagnostic criteria, that low signal intensity masses with gradual weak enhancement are benign showed 93.3% accuracy and 100% positive predictive value.
CONCLUSION: Benign solid ovarian masses tended to show low signal intensity on T2WI and gradual weak enhancement.
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 20576386     DOI: 10.1016/j.ejrad.2010.05.032

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


  3 in total

1.  Carcinosarcoma of the ovary: MR and clinical findings compared with high-grade serous carcinoma.

Authors:  Tsukasa Saida; Kensaku Mori; Yumiko Oishi Tanaka; Masafumi Sakai; Taishi Amano; Shunsuke Kikuchi; Souta Masuoka; Miki Yoshida; Tomohiko Masumoto; Toyomi Satoh; Manabu Minami
Journal:  Jpn J Radiol       Date:  2020-11-20       Impact factor: 2.374

2.  Role of diffusion-weighted magnetic resonance imaging in differentiating malignancies from benign ovarian tumors.

Authors:  Xinhua Fan; Hongbin Zhang; Shuang Meng; Jing Zhang; Chuge Zhang
Journal:  Int J Clin Exp Med       Date:  2015-11-15

3.  Magnetic Resonance Imaging Characteristics of Ovarian Clear Cell Carcinoma.

Authors:  Wei Wang; Jianhui Ding; Xiaoli Zhu; Yuan Li; Yajia Gu; Weijun Peng
Journal:  PLoS One       Date:  2015-07-10       Impact factor: 3.240

  3 in total

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