Literature DB >> 20575586

A highly convergent synthesis of tricyclic N-heterocycles coupling an Ugi reaction with a tandem S(N)2'-Heck double cyclization.

Renata Riva1, Luca Banfi, Andrea Basso, Valentina Cerulli, Giuseppe Guanti, Marcella Pani.   

Abstract

A small library of natural product-like compounds has been assembled by coupling an Ugi multicomponent reaction with two postcondensation transformations, carried out in one-pot fashion: a S(N)2' cyclization followed by an intramolecular Heck reaction.

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Year:  2010        PMID： 20575586     DOI： 10.1021/jo100859y

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthesis of fused polycyclic β-carboline derivatives using Ugi-4CR followed by cascade cyclization.

Authors:  Vipin Kumar; Anjali Saxena; Ranjan Patra; Devalina Ray; Hong-Yu Li; Biswajit Saha
Journal:  Mol Divers       Date:  2022-06-02       Impact factor: 2.943

Review 2.  Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications.

Authors:  Manar Ahmed Fouad; Hamida Abdel-Hamid; Mohammed Salah Ayoup
Journal:  RSC Adv       Date:  2020-11-23       Impact factor: 4.036

3.  Diversity-oriented synthesis of dihydrobenzoxazepinones by coupling the Ugi multicomponent reaction with a Mitsunobu cyclization.

Authors:  Lisa Moni; Luca Banfi; Andrea Basso; Alice Brambilla; Renata Riva
Journal:  Beilstein J Org Chem       Date:  2014-01-17       Impact factor: 2.883
  3 in total

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