Lan Luan1, Gang-li Wang, Rui-chao Lin. 1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China. luan9896@126.com
Abstract
OBJECTIVE: To study the chemical constituents of the extract with water from Forsythia suspensa. METHODS: The compounds were isolated and repeatedly purified on TLC, silica gel column chromatograph, gel column chromatography, and preparative HPLC, and the structures were elucidated by physico-chemical properties and NMR. RESULTS: Eight compounds were obtained and elucidated as stearic acid(I), ursolic acid(II),p-hydroxyphenyl acetic acid(III),3-(4-ehtoxoy-3-hydroxyphenyl)acrylic acid(IV),isolariciresinol(V), epipinoresinol-4-O-beta-D-glucoside(VI),(+)-epipinoresionl(VII),(+)-pinoresinol(VIII). CONCLUSION: Compound III is isolated from this genus for the first time.
OBJECTIVE: To study the chemical constituents of the extract with water from Forsythia suspensa. METHODS: The compounds were isolated and repeatedly purified on TLC, silica gel column chromatograph, gel column chromatography, and preparative HPLC, and the structures were elucidated by physico-chemical properties and NMR. RESULTS: Eight compounds were obtained and elucidated as stearic acid(I), ursolic acid(II),p-hydroxyphenyl acetic acid(III),3-(4-ehtoxoy-3-hydroxyphenyl)acrylic acid(IV),isolariciresinol(V), epipinoresinol-4-O-beta-D-glucoside(VI),(+)-epipinoresionl(VII),(+)-pinoresinol(VIII). CONCLUSION: Compound III is isolated from this genus for the first time.