Literature DB >> 20573505

Synthesis of polyhalo acridones as pH-sensitive fluorescence probes.

Chao Huang1, Sheng-Jiao Yan, Yan-Mei Li, Rong Huang, Jun Lin.   

Abstract

Polyhalo isophthalonitriles were reacted with substituted anilines and subsequently cyclocondensed in the presence of sulfuric acid to give polyhalo acridones. These polyhalo acridones were proven to be useful as pH-sensitive fluorescent probes for a wide range of acidic and basic conditions. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20573505     DOI： 10.1016/j.bmcl.2010.05.101

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  1 in total

1.  Efficient synthesis and in vivo incorporation of acridon-2-ylalanine, a fluorescent amino acid for lifetime and Förster resonance energy transfer/luminescence resonance energy transfer studies.

Authors:  Lee C Speight; Anand K Muthusamy; Jacob M Goldberg; John B Warner; Rebecca F Wissner; Taylor S Willi; Bradley F Woodman; Ryan A Mehl; E James Petersson
Journal:  J Am Chem Soc       Date:  2013-12-04       Impact factor: 15.419
  1 in total

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