Literature DB >> 20571587

Adherens junctions: from molecules to morphogenesis.

Tony J C Harris1, Ulrich Tepass.   

Abstract

How adhesive interactions between cells generate and maintain animal tissue structure remains one of the most challenging and long-standing questions in cell and developmental biology. Adherens junctions (AJs) and the cadherin-catenin complexes at their core are therefore the subjects of intense research. Recent work has greatly advanced our understanding of the molecular organization of AJs and how cadherin-catenin complexes engage actin, microtubules and the endocytic machinery. As a result, we have gained important insights into the molecular mechanisms of tissue morphogenesis.

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Year:  2010        PMID： 20571587     DOI： 10.1038/nrm2927

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  169 in total

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Review 5.  Molecular evolution of the cadherin superfamily.

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Journal:  Int J Biochem Cell Biol       Date:  2008-10-04       Impact factor: 5.085

6.  p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.

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Journal:  Cell       Date:  2006-12-01       Impact factor: 41.582

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8.  Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability.

Authors:  Marios Georgiou; Eliana Marinari; Jemima Burden; Buzz Baum
Journal:  Curr Biol       Date:  2008-10-30       Impact factor: 10.834

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Authors:  Kathryn P Harris; Ulrich Tepass
Journal:  J Cell Biol       Date:  2008-12-08       Impact factor: 10.539

10.  EPLIN regulates actin dynamics by cross-linking and stabilizing filaments.

Authors:  Raymond S Maul; Yuhong Song; Kurt J Amann; Sachi C Gerbin; Thomas D Pollard; David D Chang
Journal:  J Cell Biol       Date:  2003-02-03       Impact factor: 10.539
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7.  Cadherin selectivity filter regulates endothelial sieving properties.

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10.  Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions.

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