Markus Kraemer1, Jennifer Uekermann, Jens Wiltfang, Bernhard Kis. 1. Outpatient Clinic for Adult ADHD, Department of Psychiatry and Psychotherapy, University of Duisburg-Essen, LVR Clinic Essen; and daggerDepartment of Neurology, Alfried Krupp Hospital Essen, Essen, Germany. markus.kraemer@krupp-krankenhaus.de
Abstract
OBJECTIVE: We present 3 new cases of psychotic symptoms in patients with adult attention-deficit/hyperactivity disorder while regularly treated with a stimulant therapy with methylphenidate. METHODS: Existing literature about this theme is reviewed, and potential mechanisms are discussed. RESULTS AND CONCLUSIONS: Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate.
OBJECTIVE: We present 3 new cases of psychotic symptoms in patients with adult attention-deficit/hyperactivity disorder while regularly treated with a stimulant therapy with methylphenidate. METHODS: Existing literature about this theme is reviewed, and potential mechanisms are discussed. RESULTS AND CONCLUSIONS: Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate.
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