Literature DB >> 20570493

Psychiatrists' attitude to antipsychotic depot treatment in patients with first-episode schizophrenia.

S Heres1, T Reichhart, J Hamann, R Mendel, S Leucht, W Kissling.   

Abstract

OBJECTIVE: Despite good clinical evidence, depot antipsychotics are only seldom prescribed to patients with first episode schizophrenia. The present study aims at investigating psychiatrists' reasons for this reservation.
METHOD: We surveyed 198 psychiatrists on their attitude toward offering depot treatment to first episode patients (FEP). Participants scored the extent of influence of individual factors on their decision on a seven-point-scale, additional data on their prescription practice and estimation of the relapse risk of FEP were collected.
RESULTS: Psychiatrists reported that only three out of 12 factors were of influence. These were the limited availability of different second generation antipsychotic depot drugs, the frequent rejection of the depot offer by the patients and the patients' skepticism based on the lack in experience of a relapse.
CONCLUSIONS: There is actually little specific reason for not prescribing depot to FEP according to the current survey. For those factors being reported to be of influence, psychoeducation, including profound information on depot treatment, the development of additional SGA depot drugs and the standard offer of depot treatment to all FEP in a shared-decision-making may be considered.
Copyright © 2010 Elsevier Masson SAS. All rights reserved.

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Year:  2010        PMID: 20570493     DOI: 10.1016/j.eurpsy.2009.12.020

Source DB:  PubMed          Journal:  Eur Psychiatry        ISSN: 0924-9338            Impact factor:   5.361


  24 in total

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Authors:  Amlan K Das; Abid Malik; Peter M Haddad
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2.  Should we listen and talk more to our patients?

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Journal:  World Psychiatry       Date:  2013-10       Impact factor: 49.548

3.  Indications for and use of long-acting injectable antipsychotics: consideration from an inpatient setting.

Authors:  Taishiro Kishimoto; Sohag Sanghani; Mark J Russ; Akeem N Marsh; Joshua Morris; Suparna Basu; Majnu John; John M Kane
Journal:  Int Clin Psychopharmacol       Date:  2017-05       Impact factor: 1.659

4.  The knowledge and attitudes of psychiatrists towards antipsychotic long-acting injections in Nigeria.

Authors:  Bawo O James; Joyce O Omoaregba; Kingsley M Okonoda; Edebi U Otefe; Maxine X Patel
Journal:  Ther Adv Psychopharmacol       Date:  2012-10

Review 5.  Barriers to the Use of Long-Acting Injectable Antipsychotics in the Management of Schizophrenia.

Authors:  Eduard Parellada; Miquel Bioque
Journal:  CNS Drugs       Date:  2016-08       Impact factor: 5.749

6.  Patients' and clinicians' attitude towards long-acting depot antipsychotics in subjects with a first episode of psychosis.

Authors:  Matthias Kirschner; Anastasia Theodoridou; Paolo Fusar-Poli; Stefan Kaiser; Matthias Jäger
Journal:  Ther Adv Psychopharmacol       Date:  2013-04

7.  Antipsychotic therapeutic drug monitoring: psychiatrists' attitudes and factors predicting likely future use.

Authors:  Suzanne Law; Peter M Haddad; Imran B Chaudhry; Nusrat Husain; Richard J Drake; Robert J Flanagan; Anthony S David; Maxine X Patel
Journal:  Ther Adv Psychopharmacol       Date:  2015-08

8.  Comparison of Long-Acting Injectable Antipsychotics With Oral Antipsychotics and Suicide and All-Cause Mortality in Patients With Newly Diagnosed Schizophrenia.

Authors:  Cheng-Yi Huang; Su-Chen Fang; Yu-Hsuan Joni Shao
Journal:  JAMA Netw Open       Date:  2021-05-03

9.  Treatment adherence with early prescription of long-acting injectable antipsychotics in recent-onset schizophrenia.

Authors:  Annie Viala; Françoise Cornic; Marie-Noëlle Vacheron
Journal:  Schizophr Res Treatment       Date:  2012-04-03

10.  Role of long-acting injectable second-generation antipsychotics in the treatment of first-episode schizophrenia: a clinical perspective.

Authors:  Radovan Přikryl; Hana Přikrylová Kučerová; Michaela Vrzalová; Eva Cešková
Journal:  Schizophr Res Treatment       Date:  2012-05-07
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