Pharmacotherapy of prostatitis.

IMPORTANCE OF THE FIELD: Prostatitis is a prevalent and morbid condition with a significant impact on a patient's quality of life. The four distinct prostatitis syndromes have different pathophysiologies, therapy and prognosis. Acute and chronic bacterial prostatitis is best treated with appropriate antibiotics that penetrate the prostate and kill the causative organisms. The most challenging category to treat is category III or chronic prostatitis/chronic pelvic pain syndrome. AREAS COVERED IN THE REVIEW: This review covers the categories of prostatitis and currently recommended therapies, as well as novel approaches on the horizon. WHAT THE READER WILL GAIN: Knowledge of the current framework for the diagnosis and management of the diverse prostatitis spectrum. TAKE HOME MESSAGE: Prostatitis is a diverse group of syndromes. Chronic prostatitis/chronic pelvic pain syndrome is a multifactorial syndrome that requires a multimodal approach to effectively treat the patient. The UPOINT technique is used to clinically phenotype these patients and drive the selection of multimodal therapy.