Literature DB >> 20567163

Overlapping compared with end-to-end repair of third- and fourth-degree obstetric anal sphincter tears: a randomized controlled trial.

Scott A Farrell1, Donna Gilmour, Geoffrey K Turnbull, Matthias H Schmidt, Thomas F Baskett, Gordon Flowerdew, Cora A Fanning.   

Abstract

OBJECTIVE: To compare overlapping repair with end-to-end repair of obstetric tears and to investigate which procedure results in a higher rate of flatal incontinence.
METHODS: One-hundred forty-nine primiparous women sustaining a complete third- or a fourth-degree tear of the perineum were assigned randomly to a primary sphincter repair using either an end-to-end (n=75) or an overlapping surgical technique (n=74) using 3-0 polyglyconate. Outcome measures at 6 months included rates of flatal and fecal incontinence, quality-of-life scores, integrity of the internal and external anal sphincters by anal ultrasonography, and anal sphincter function as reflected by anal manometry.
RESULTS: Women who underwent overlapping repair compared with end-to-end repair had higher rates of flatal incontinence, 61% compared with 39% (odds ratio [OR] 2.44, confidence interval [CI] 1.2-5.0). The rate of fecal incontinence was also higher, 15% compared with 8% (OR 1.97, CI 0.62-6.3) but did not attain statistical significance. Rates of internal and external anal sphincter defects did not differ significantly between groups and did not correlate with anal incontinence symptoms. Fecal incontinence was higher when there was a defect in both sphincter muscles. Anal sphincter function as assessed by manometry did not differ significantly between groups.
CONCLUSION: End-to-end repair of third- or fourth-degree obstetric anal sphincter tears is associated with lower rates of anal incontinence when compared with overlapping repair. CLINICAL TRIAL REGISTRATION: ISRCTN Register, isrctn.org, ISRCTN04149919. LEVEL OF EVIDENCE: I.

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Year:  2010        PMID: 20567163     DOI: 10.1097/AOG.0b013e3181e366ef

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  8 in total

1.  Management of 3rd and 4th Degree Perineal Tears after Vaginal Birth. German Guideline of the German Society of Gynecology and Obstetrics (AWMF Registry No. 015/079, October 2014).

Authors:  T Aigmueller; W Bader; K Beilecke; K Elenskaia; A Frudinger; E Hanzal; H Helmer; H Huemer; M van der Kleyn; D Koelle; S Kropshofer; J Pfeiffer; C Reisenauer; A Tammaa; K Tamussino; W Umek
Journal:  Geburtshilfe Frauenheilkd       Date:  2015-02       Impact factor: 2.915

Review 2.  Surgery for faecal incontinence in adults.

Authors:  Steven R Brown; Himanshu Wadhawan; Richard L Nelson
Journal:  Cochrane Database Syst Rev       Date:  2013-07-02

Review 3.  Recent advances in functional anorectal disorders.

Authors:  Adil E Bharucha
Journal:  Curr Gastroenterol Rep       Date:  2011-08

4.  [Pelvic floor disorders from the surgeon's viewpoint].

Authors:  T H Schiedeck
Journal:  Chirurg       Date:  2013-10       Impact factor: 0.955

5.  Tools for fecal incontinence assessment: lessons for inflammatory bowel disease trials based on a systematic review.

Authors:  Ferdinando D'Amico; Steven D Wexner; Carolynne J Vaizey; Célia Gouynou; Silvio Danese; Laurent Peyrin-Biroulet
Journal:  United European Gastroenterol J       Date:  2020-07-17       Impact factor: 4.623

Review 6.  Patient-reported outcomes and outcome measures in childbirth perineal trauma research: a systematic review.

Authors:  Stergios K Doumouchtsis; Jemina Loganathan; John Fahmy; Gabriele Falconi; Maria Rada; Abdullatif Elfituri; Jorge Milhem Haddad; Vasilios Pergialiotis; Cornelia Betschart
Journal:  Int Urogynecol J       Date:  2021-06-18       Impact factor: 2.894

Review 7.  Colorectal-Vaginal Fistulas: Imaging and Novel Interventional Treatment Modalities.

Authors:  M-Grace Knuttinen; Johnny Yi; Paul Magtibay; Christina T Miller; Sadeer Alzubaidi; Sailendra Naidu; Rahmi Oklu; J Scott Kriegshauser; Winnie A Mar
Journal:  J Clin Med       Date:  2018-04-22       Impact factor: 4.241

Review 8.  Non-compliance with randomised allocation and missing outcome data in randomised controlled trials evaluating surgical interventions: a systematic review.

Authors:  Temitope E Adewuyi; Graeme MacLennan; Jonathan A Cook
Journal:  BMC Res Notes       Date:  2015-09-02
  8 in total

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