Literature DB >> 205668

Integrated viral DNA sequences in Epstein-Barr virus-converted human lymphoma lines.

M Andersson-Anvret, T Lindahl.   

Abstract

Most human lymphoid cell lines contain multiple copies of circular, nonintegrated Epstein-Barr virus (EBV) DNA molecules as well as viral DNA sequences with properties of integrated DNA. The physical state of the EBV DNA in a human lymphoma line that only contains one virus genome equivalent per cell has now been studied by three different methods, neutral CsCl density gradient centrifugation, actinomycin D-CsCl gradient centrifugation, and Hirt fractionation. This cell line, AW-Ramos, has been obtained by EBV infection in vitro of the apparently EBV-negative Ramos lymphoma line. The results indicate that the EBV DNA in AW-Ramos is present exclusively in a linearly integrated form. Similar data were obtained with two other EBV-converted sublines of Ramos cells.

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Year:  1978        PMID： 205668      PMCID： PMC525964     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  37 in total

1.  MOLECULAR MECHANISMS OF GENETIC RECOMBINATION IN BACTERIOPHAGE. II. JOINING OF PARENTAL DNA MOLECULES OF PHAGE T4.

Authors:  J I TOMIZAWA; N ANRAKU
Journal:  J Mol Biol       Date:  1964-04       Impact factor: 5.469

2.  MOLECULAR MECHANISMS OF GENETIC RECOMBINATION IN BACTERIOPHAGE. IV. ABSENCE OF POLYNUCLEOTIDE INTERRUPTION IN DNA OF T4 AND LAMBDA PHAGE PARTICLES, WITH SPECIAL REFERENCE TO HETEROZYGOSIS.

Authors:  J TOMIZAWA; N ANRAKU
Journal:  J Mol Biol       Date:  1965-03       Impact factor: 5.469

3.  Heterogeneity of Epstein-Barr virus originating from P3HR-1 cells. I. Studies on EBNA induction.

Authors:  K O Fresen; B Merkt; G W Bornkamm; H Hausen
Journal:  Int J Cancer       Date:  1977-03-15       Impact factor: 7.396

4.  Intracellular forms of Epstein-Barr virus DNA in Raji cells.

Authors:  A Adams; T Lindahl
Journal:  IARC Sci Publ       Date:  1975

5.  The arrangement of simian virus 40 sequences in the DNA of transformed cells.

Authors:  M Botchan; W Topp; J Sambrook
Journal:  Cell       Date:  1976-10       Impact factor: 41.582

6.  Isolation of herpes simplex virus DNA from the "hirt supernatant".

Authors:  M M Pater; R W Hyman; F Rapp
Journal:  Virology       Date:  1976-12       Impact factor: 3.616

7.  Formation and structure of infectious DNA of spleen necrosis virus.

Authors:  E Fritsch; H M Temin
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

8.  Tumorigenicity of human hematopoietic cell lines in athymic nude mice.

Authors:  K Nilsson; B C Giovanella; J S Stehlin; G Klein
Journal:  Int J Cancer       Date:  1977-03-15       Impact factor: 7.396

9.  Human lymphoblastoid cell lines derived from individuals without lymphoproliferative disease contain the same latent forms of Epstein-Barr virus DNA as those found in tumor cells.

Authors:  C Kaschka-Dierich; L Falk; G Bjursell; A Adams; T Lindahl
Journal:  Int J Cancer       Date:  1977-08-15       Impact factor: 7.396

10.  Integrated viral sequences in adenovirus type 12-transformed hamster cells.

Authors:  J Groneberg; Y Chardonnet; W Doerfler
Journal:  Cell       Date:  1977-01       Impact factor: 41.582
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  23 in total

1.  Epstein-Barr virus (EBV)-negative B-lymphoma cell lines for clonal isolation and replication of EBV recombinants.

Authors:  A Marchini; R Longnecker; E Kieff
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

2.  Persistence of the cytomegalovirus genome in human cells.

Authors:  E S Mocarski; M F Stinski
Journal:  J Virol       Date:  1979-09       Impact factor: 5.103

3.  Epstein-Barr virus-specific RNA. III. Mapping of DNA encoding viral RNA in restringent infection.

Authors:  A L Powell; W King; E Kieff
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

4.  Epstein-Barr virus genomes in lymphoid cells: activation in mitosis and chromosomal location.

Authors:  C G Teo; B E Griffin
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene.

Authors:  U Zimber-Strobl; K O Suentzenich; G Laux; D Eick; M Cordier; A Calender; M Billaud; G M Lenoir; G W Bornkamm
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

6.  Random association of Epstein-Barr virus genomes with host cell metaphase chromosomes in Burkitt's lymphoma-derived cell lines.

Authors:  A Harris; B D Young; B E Griffin
Journal:  J Virol       Date:  1985-10       Impact factor: 5.103

7.  Nucleosomal structure of Epstein-Barr virus DNA in transformed cell lines.

Authors:  J E Shaw; L F Levinger; C W Carter
Journal:  J Virol       Date:  1979-02       Impact factor: 5.103

8.  Epstein-Barr virus (EBV) recombinants: use of positive selection markers to rescue mutants in EBV-negative B-lymphoma cells.

Authors:  F Wang; A Marchini; E Kieff
Journal:  J Virol       Date:  1991-04       Impact factor: 5.103

9.  When Epstein-Barr virus persistently infects B-cell lines, it frequently integrates.

Authors:  E A Hurley; S Agger; J A McNeil; J B Lawrence; A Calendar; G Lenoir; D A Thorley-Lawson
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

10.  Oncogenic transformation by by equine herpesviruses. II. Coestablishment of persistent infection and oncogenic transformation of hamster embryo cells by equine herpesvirus type 1 preparations enriched for defective interfering particles.

Authors:  R A Robinson; R B Vance; D J O'Callaghan
Journal:  J Virol       Date:  1980-10       Impact factor: 5.103
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