Literature DB >> 20565486

Fourteen-year-old girl with endobronchial carcinoid tumour presenting with asthma and lobar emphysema.

Julie Bjerglund Andersen1, Jann Mortensen, Karen Damgaard, Marianne Skov, Jørgen Sparup, Bodil Laub Petersen, Catherine Rechnitzer, Lise Borgwardt.   

Abstract

INTRODUCTION: Bronchial carcinoid tumours seldom occur in children, and represent a rare cause of pulmonary obstruction. Because of low clinical suspicion and the variable ways of presentation, diagnosis may be delayed.
OBJECTIVES: We report on a patient with this tumour. It is hoped that increased awareness of the tumour can lead to earlier diagnosis.
METHODS: Report of a case.
RESULTS: This case describes a 14-year-old previously healthy girl, presenting with asthma-like symptoms throughout 2 years, decreased lung function and emphysema in left lower lobe on chest x-ray. Computerized tomography (CT) showed an intraluminal process in the left main bronchus and emphysema in both the upper and lower left lobe and showed no signs of metastasis or spread to lung tissue. Bronchoscopy showed an inflammatory polyp. Surgical resection demonstrated a typical carcinoid tumour. Later control biopsy revealed no persisting malignant tissue. The asthma symptoms returned and a new bronchoscopy showed scarring and narrowing of the left bronchus. Treatment comprised of dilatation by bronchoscopy plus daily combination corticosteroids and beta-2-agonist inhalation and the symptoms improved. No signs of relapse 16 months postdiagnosis.
CONCLUSIONS: The case clearly shows the delay, which is common in the diagnosis of children with bronchial carcinoid tumours. Symptoms of the obstructive nature of the tumour are variable and might present as emphysema seen on x-ray and CT. Carcinoid tumour should be considered in children with longstanding pulmonary symptoms with no response to conventional treatment. Prognosis is good but long-term follow up is needed.

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Year:  2010        PMID: 20565486     DOI: 10.1111/j.1752-699X.2009.00149.x

Source DB:  PubMed          Journal:  Clin Respir J        ISSN: 1752-6981            Impact factor:   2.570


  3 in total

1.  Endobronchial tumor in children: Unusual finding in recurrent pneumonia, report of three cases.

Authors:  Silvia Madafferi; Vincenzo D Catania; Antonella Accinni; Renata Boldrini; Alessandro Inserra
Journal:  World J Clin Pediatr       Date:  2015-05-08

Review 2.  Overdiagnosis of a typical carcinoid tumor as an adenocarcinoma of the lung: a case report and review of the literature.

Authors:  Ilhan Demirci; Susanne Herold; Andreas Kopp; Michael Flaßhove; Bernd Klosterhalfen; Hermann Janßen
Journal:  World J Surg Oncol       Date:  2012-01-23       Impact factor: 2.754

3.  Bronchoscopic management of endobronchial carcinoid presenting as asthma Mimic.

Authors:  Ayman Rizk; Mohamed A Salam; Engy Elnahas; Hasnaa Fekry; Mohamed Salem; Marwa Magdy; Mohamed Zidan; Ayman Nosseir; Yasser Eldowik; Adel Kotb; Mahmoud Ibrahim Mahmoud; Hatem Elmallawany
Journal:  Respir Med Case Rep       Date:  2020-02-10
  3 in total

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