Literature DB >> 2056310

Synthesis, characterization, and in vitro cytotoxic effects of K4 [PtCl2ATP].

K K Nayak1, R Bhattacharyya, P Maity.   

Abstract

An antineoplastic agent, cis-K4 [PtCl2ATP] has been synthesized and characterized, using elemental analysis, solution conductance, thermoanalysis, infrared, NMR spectroscopy, and circular dichroism studies. The in vitro cytotoxic effect imparted by this compound on Dalton's Lymphoma cells has been assessed by Trypan blue dye exclusion method and 51Cr release assays.

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Year:  1991        PMID: 2056310     DOI: 10.1016/0162-0134(91)80022-a

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN: 0162-0134            Impact factor:   4.155


  1 in total

1.  Histological vis-a-vis biochemical assessment on the toxic level and antineoplastic efficacy of a synthetic drug Pt-ATP on experimental animal models.

Authors:  Shipra Pal; Arpita Sengupta Sadhu; Swarup Patra; Kalyan K Mukherjea
Journal:  J Exp Clin Cancer Res       Date:  2008-11-12
  1 in total

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