Literature DB >> 20561817

New models for cancer research: human cancer stem cell xenografts.

Marta Baiocchi1, Mauro Biffoni, Lucia Ricci-Vitiani, Emanuela Pilozzi, Ruggero De Maria.   

Abstract

Human cancer stem cells represent promising tools for new approaches to pathway-targeted drug discovery and preclinical screening. Because of their distinctive capability to recapitulate the development of the original tumors in vivo, the study of human cancer stem cells (CSCs) largely relies on models of xenograft transplantation into immunodeficient mice. In this frame, immunity and microenvironment-related issues need careful consideration. Here we shortly revise present knowledge on xenograft-related aspects of human CSCs studies. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20561817     DOI: 10.1016/j.coph.2010.05.002

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN: 1471-4892            Impact factor:   5.547


  20 in total

Review 1.  The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute.

Authors:  Jilong Yang; Zhiwu Ren; Xiaoling Du; Mengze Hao; Wenya Zhou
Journal:  Stem Cell Investig       Date:  2014-10-27

Review 2.  Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs.

Authors:  María Antonia Lizarbe; Jorge Calle-Espinosa; Eva Fernández-Lizarbe; Sara Fernández-Lizarbe; Miguel Ángel Robles; Nieves Olmo; Javier Turnay
Journal:  Biomed Res Int       Date:  2017-05-10       Impact factor: 3.411

3.  Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance.

Authors:  Maria Laura De Angelis; Ann Zeuner; Eleonora Policicchio; Giorgio Russo; Alessandro Bruselles; Michele Signore; Sara Vitale; Gabriele De Luca; Emanuela Pilozzi; Alessandra Boe; Giorgio Stassi; Lucia Ricci-Vitiani; Carla Azzurra Amoreo; Alfredo Pagliuca; Federica Francescangeli; Marco Tartaglia; Ruggero De Maria; Marta Baiocchi
Journal:  Stem Cells Transl Med       Date:  2016-03-08       Impact factor: 6.940

4.  Depletion of Mouse Cells from Human Tumor Xenografts Significantly Improves Downstream Analysis of Target Cells.

Authors:  David J Agorku; Stefan Tomiuk; Kerstin Klingner; Stefan Wild; Silvia Rüberg; Lisa Zatrieb; Andreas Bosio; Julia Schueler; Olaf Hardt
Journal:  J Vis Exp       Date:  2016-07-29       Impact factor: 1.355

5.  Elimination of quiescent/slow-proliferating cancer stem cells by Bcl-XL inhibition in non-small cell lung cancer.

Authors:  A Zeuner; F Francescangeli; P Contavalli; G Zapparelli; T Apuzzo; A Eramo; M Baiocchi; M L De Angelis; M Biffoni; G Sette; M Todaro; G Stassi; R De Maria
Journal:  Cell Death Differ       Date:  2014-07-18       Impact factor: 15.828

6.  Therapeutic targeting of cancer stem cells.

Authors:  Marcello Maugeri-Saccà; Ann Zeuner; Ruggero De Maria
Journal:  Front Oncol       Date:  2011-06-17       Impact factor: 6.244

7.  Experimental gastric carcinogenesis in Cebus apella nonhuman primates.

Authors:  Joana de Fátima Ferreira Borges da Costa; Mariana Ferreira Leal; Tanielly Cristina Raiol Silva; Edilson Ferreira Andrade Junior; Alexandre Pingarilho Rezende; José Augusto Pereira Carneiro Muniz; Antonio Carlos Cunha Lacreta Junior; Paulo Pimentel Assumpção; Danielle Queiroz Calcagno; Samia Demachki; Silvia Helena Barem Rabenhorst; Marília de Arruda Cardoso Smith; Rommel Rodriguez Burbano
Journal:  PLoS One       Date:  2011-07-21       Impact factor: 3.240

8.  Sarcoma stem cells: do we know what we are looking for?

Authors:  Matteo Trucco; David Loeb
Journal:  Sarcoma       Date:  2012-05-09

9.  Defining the critical hurdles in cancer immunotherapy.

Authors:  Bernard A Fox; Dolores J Schendel; Lisa H Butterfield; Steinar Aamdal; James P Allison; Paolo Antonio Ascierto; Michael B Atkins; Jirina Bartunkova; Lothar Bergmann; Neil Berinstein; Cristina C Bonorino; Ernest Borden; Jonathan L Bramson; Cedrik M Britten; Xuetao Cao; William E Carson; Alfred E Chang; Dainius Characiejus; A Raja Choudhury; George Coukos; Tanja de Gruijl; Robert O Dillman; Harry Dolstra; Glenn Dranoff; Lindy G Durrant; James H Finke; Jerome Galon; Jared A Gollob; Cécile Gouttefangeas; Fabio Grizzi; Michele Guida; Leif Håkansson; Kristen Hege; Ronald B Herberman; F Stephen Hodi; Axel Hoos; Christoph Huber; Patrick Hwu; Kohzoh Imai; Elizabeth M Jaffee; Sylvia Janetzki; Carl H June; Pawel Kalinski; Howard L Kaufman; Koji Kawakami; Yutaka Kawakami; Ulrich Keilholtz; Samir N Khleif; Rolf Kiessling; Beatrix Kotlan; Guido Kroemer; Rejean Lapointe; Hyam I Levitsky; Michael T Lotze; Cristina Maccalli; Michele Maio; Jens-Peter Marschner; Michael J Mastrangelo; Giuseppe Masucci; Ignacio Melero; Cornelius Melief; William J Murphy; Brad Nelson; Andrea Nicolini; Michael I Nishimura; Kunle Odunsi; Pamela S Ohashi; Jill O'Donnell-Tormey; Lloyd J Old; Christian Ottensmeier; Michael Papamichail; Giorgio Parmiani; Graham Pawelec; Enrico Proietti; Shukui Qin; Robert Rees; Antoni Ribas; Ruggero Ridolfi; Gerd Ritter; Licia Rivoltini; Pedro J Romero; Mohamed L Salem; Rik J Scheper; Barbara Seliger; Padmanee Sharma; Hiroshi Shiku; Harpreet Singh-Jasuja; Wenru Song; Per Thor Straten; Hideaki Tahara; Zhigang Tian; Sjoerd H van Der Burg; Paul von Hoegen; Ena Wang; Marij Jp Welters; Hauke Winter; Tara Withington; Jedd D Wolchok; Weihua Xiao; Laurence Zitvogel; Heinz Zwierzina; Francesco M Marincola; Thomas F Gajewski; Jon M Wigginton; Mary L Disis
Journal:  J Transl Med       Date:  2011-12-14       Impact factor: 5.531

10.  Cancer stem cells in pediatric sarcomas.

Authors:  Filemon S Dela Cruz
Journal:  Front Oncol       Date:  2013-06-27       Impact factor: 6.244

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