Literature DB >> 20561321

Cross-sectional study of the prevalence of radiographic degenerative joint disease in domesticated cats.

B Duncan X Lascelles1, John B Henry, James Brown, Ian Robertson, Andrea Thomson Sumrell, Wendy Simpson, Simon Wheeler, Bernie D Hansen, Helia Zamprogno, Mila Freire, Anthony Pease.   

Abstract

OBJECTIVE: To determine the prevalence of radiographic signs of degenerative joint disease (DJD) in a randomly selected sample of domestic cats. STUDY
DESIGN: Prospective observational study. ANIMALS: Client-owned cats.
METHODS: Cats (n=100) from a single practice and equally distributed across 4 age groups (0-5; 5-10; 10-15, and 15-20 years old) were randomly selected (regardless of heath status) and sedated for orthogonal radiographic projections of all joints and the spine. Quasi-Poisson regression analysis was used to investigate the relationship between patient demographics, blood biochemistry, hematologic and urine analysis variables, and DJD severity.
RESULTS: Most (92%) cats had radiographic evidence of DJD; 91% had at least 1 site of appendicular DJD and 55% had > or = 1 site of axial column DJD. Affected joints in descending order of frequency were hip, stifle, tarsus, and elbow. The thoracic segment of the spine was more frequently affected than the lumbosacral segment. Although many variables were significantly associated with DJD, when variables were combined, only the association between age and DJD was significant (P<.0001). For each 1-year increase in cat age, the expected total DJD score increases by an estimated 13.6% (95% confidence interval: 10.6%, 16.8%).
CONCLUSION: Radiographically visible DJD is very common in domesticated cats, even in young animals and is strongly associated with age. CLINICAL RELEVANCE: DJD is a common disease of domesticated cats that requires further investigation of its associated clinical signs.

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Year:  2010        PMID: 20561321     DOI: 10.1111/j.1532-950X.2010.00708.x

Source DB:  PubMed          Journal:  Vet Surg        ISSN: 0161-3499            Impact factor:   1.495


  26 in total

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2.  Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain.

Authors:  Margaret E Gruen; Kristen M Messenger; Andrea E Thomson; Emily H Griffith; Lauren A Aldrich; Shelly Vaden; B Duncan X Lascelles
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5.  Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies.

Authors:  Christina L Marino; B Duncan X Lascelles; Shelly L Vaden; Margaret E Gruen; Steven L Marks
Journal:  J Feline Med Surg       Date:  2013-11-11       Impact factor: 2.015

6.  Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats.

Authors:  B Duncan X Lascelles; Yaa-Hui Dong; Denis J Marcellin-Little; Andrea Thomson; Simon Wheeler; Maria Correa
Journal:  BMC Vet Res       Date:  2012-01-27       Impact factor: 2.741

7.  Criterion Validation Testing of Clinical Metrology Instruments for Measuring Degenerative Joint Disease Associated Mobility Impairment in Cats.

Authors:  Margaret E Gruen; Emily H Griffith; Andrea E Thomson; Wendy Simpson; B Duncan X Lascelles
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8.  Relationship between degenerative joint disease, pain, and Bartonella spp. seroreactivity in domesticated cats.

Authors:  A Tomas; E L Pultorak; M E Gruen; E B Breitschwerdt; B D X Lascelles
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9.  Histological and molecular characterisation of feline humeral condylar osteoarthritis.

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Journal:  BMC Vet Res       Date:  2013-06-04       Impact factor: 2.741

10.  Preliminary Validation and Reliability Testing of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians, in a Colony of Laboratory Cats.

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