Literature DB >> 20559925

Engineered heart tissue: high throughput platform for dissection of complex diseases.

Jozef Lazar1, Howard J Jacob, Tetsuro Wakatsuki.   

Abstract

The polygenic nature of resistance/sensitivity of the heart to ischemia is generally accepted. Unfortunately, little is known about gene(s) involved in response to this insult. The goal of present study is to introduce new tool, engineered heart tissue (EHT), for accelerating positional cloning and for providing novel functional assays.

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Year:  2008        PMID： 20559925     DOI： 10.1007/s12265-008-9026-0

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN： 1937-5387            Impact factor:   4.132


  14 in total

1.  S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts.

Authors:  Andrew Remppis; Sven T Pleger; Patrick Most; Jan Lindenkamp; Philipp Ehlermann; Christopher Schweda; Eva Löffler; Dieter Weichenhan; Wolfram Zimmermann; Thomas Eschenhagen; Walter J Koch; Hugo A Katus
Journal:  J Gene Med       Date:  2004-04       Impact factor: 4.565

Review 2.  Phenotypic screening for pharmaceuticals using tissue constructs.

Authors:  T Wakatsuki; J A Fee; E L Elson
Journal:  Curr Pharm Biotechnol       Date:  2004-04       Impact factor: 2.837

Review 3.  Tissue engineering in the USA.

Authors:  R M Nerem
Journal:  Med Biol Eng Comput       Date:  1992-07       Impact factor: 2.602

Review 4.  Engineering myocardial tissue.

Authors:  Thomas Eschenhagen; Wolfram H Zimmermann
Journal:  Circ Res       Date:  2005-12-09       Impact factor: 17.367

5.  Reconstitution of the Frank-Starling mechanism in engineered heart tissues.

Authors:  Clara F Asnes; J Pablo Marquez; Elliot L Elson; Tetsuro Wakatsuki
Journal:  Biophys J       Date:  2006-06-16       Impact factor: 4.033

Review 6.  Expression genetics and the phenotype revolution.

Authors:  Robert W Williams
Journal:  Mamm Genome       Date:  2006-06-12       Impact factor: 2.957

Review 7.  Antibody microarrays: current status and key technological advances.

Authors:  Christer Wingren; Carl A K Borrebaeck
Journal:  OMICS       Date:  2006

Review 8.  Tissue engineering: a new frontier in physiological genomics.

Authors:  Matthew C Petersen; Jozef Lazar; Howard J Jacob; Tetsuro Wakatsuki
Journal:  Physiol Genomics       Date:  2007-10-23       Impact factor: 3.107

9.  Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: role of nitric oxide synthase and Hsp90.

Authors:  Yang Shi; William Hutchins; Hitoshi Ogawa; Chung-Che Chang; Kirkwood A Pritchard; Chenyang Zhang; Pawjai Khampang; Jozef Lazar; Howard J Jacob; Parvaneh Rafiee; John E Baker
Journal:  J Mol Cell Cardiol       Date:  2005-04       Impact factor: 5.000

10.  A DNA microarray survey of gene expression in normal human tissues.

Authors:  Radha Shyamsundar; Young H Kim; John P Higgins; Kelli Montgomery; Michelle Jorden; Anand Sethuraman; Matt van de Rijn; David Botstein; Patrick O Brown; Jonathan R Pollack
Journal:  Genome Biol       Date:  2005-02-14       Impact factor: 13.583
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