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Literature DB >> 20559914

Stem cell therapy trials: a call for standardization.

Abstract

There are currently 25 new clinical cellular therapy trials in progress for cardiovascular disease in the US, and a similar number ongoing in Europe. The lack of standardization in cell isolation, preparation, storage, and time and localization of delivery, present clear hurdles to this growing field. This emphasizes the need for an organized task force to work closely with the FDA to agree upon standardized methods with the end result being improvements in patient care and enhanced knowledge in the field.

Entities: Disease Species

Mesh：

Year: 2008 PMID： 20559914 DOI： 10.1007/s12265-008-9042-0

Source DB: PubMed Journal: J Cardiovasc Transl Res ISSN： 1937-5387 Impact factor: 4.132

19 in total

Review 1. Unchain my heart: the scientific foundations of cardiac repair.

Authors: Stefanie Dimmeler; Andreas M Zeiher; Michael D Schneider
Journal: J Clin Invest Date: 2005-03 Impact factor: 14.808

2. Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings.

Authors: Hans F R Dohmann; Emerson C Perin; Christina M Takiya; Guilherme V Silva; Suzana A Silva; Andre L S Sousa; Claudio T Mesquita; Maria-Isabel D Rossi; Bernardo M O Pascarelli; Isabella M Assis; Helio S Dutra; João A R Assad; Rodrigo V Castello-Branco; Cantidio Drummond; Hans J F Dohmann; James T Willerson; Radovan Borojevic
Journal: Circulation Date: 2005-07-18 Impact factor: 29.690

Review 3. Methods of stem cell delivery in cardiac diseases.

Authors: Emerson C Perin; Javier López
Journal: Nat Clin Pract Cardiovasc Med Date: 2006-03

Review 4. Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety Monitoring.

Authors: Peter Oettgen; Andrew J Boyle; Steven P Schulman; Joshua M Hare
Journal: Circulation Date: 2006-07-25 Impact factor: 29.690

5. Cardiac cell therapy--mixed results from mixed cells.

Authors: Anthony Rosenzweig
Journal: N Engl J Med Date: 2006-09-21 Impact factor: 91.245

6. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart.

Authors: Jozef Bartunek; Stephanie Dimmeler; Helmut Drexler; Francisco Fernández-Avilés; Manuel Galinanes; Stefan Janssens; John Martin; Anthony Mathur; Phillipe Menasche; Sylvia Priori; Bodo Strauer; Michal Tendera; William Wijns; Andreas Zeiher
Journal: Eur Heart J Date: 2006-03-16 Impact factor: 29.983

7. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.

Authors: Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Journal: N Engl J Med Date: 2006-09-21 Impact factor: 91.245

8. Good manufacturing practice-compliant validation and preparation of BM cells for the therapy of acute myocardial infarction.

Authors: C Griesel; H-G Heuft; D Herrmann; A Franke; D Ladas; N Stiehler; A Stucki; M Braun; K C Wollert; G P Meyer; H Drexler; B Hertenstein; A Ganser; W Rüdinger; L Arseniev
Journal: Cytotherapy Date: 2007 Impact factor: 5.414

9. Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.

Authors: Florian H Seeger; Torsten Tonn; Nicola Krzossok; Andreas M Zeiher; Stefanie Dimmeler
Journal: Eur Heart J Date: 2007-02-13 Impact factor: 29.983

Stem cell therapy trials: a call for standardization.

Review 1. Unchain my heart: the scientific foundations of cardiac repair.

2. Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings.

Review 3. Methods of stem cell delivery in cardiac diseases.

Review 4. Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety Monitoring.

5. Cardiac cell therapy--mixed results from mixed cells.

6. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart.

7. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.

8. Good manufacturing practice-compliant validation and preparation of BM cells for the therapy of acute myocardial infarction.

9. Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.

10. Regenerating functional myocardium: improved performance after skeletal myoblast transplantation.

1. Oversight and management of a cell therapy clinical trial network: experience and lessons learned.

2. Translating research into clinical scale manufacturing of mesenchymal stromal cells.

Review 3. Cardiac cell repair therapy: a clinical perspective.

4. Mesenchymal stem cells for cardiac regeneration: translation to bedside reality.