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Literature DB >> 20559720

Stem cells in the diabetic infarcted heart.

Carley E Glass¹, Pawan K Singal, Dinender K Singla.

Abstract

Diabetes mellitus is one of the leading causes of death, and the majority of these deaths are associated with cardiovascular diseases. Development and progression of myocardial infarction leading to heart failure is much more complex and multifactorial in diabetics compared with non-diabetics. Despite significant advances in pharmacological interventions and surgical techniques, the disease progression leading to diabetic end-stage heart failure remains very high. Recently, cell therapy has gained much attention as an alternative approach to treat various heart diseases. However, transplanted stem cell studies in diabetic animal models are very limited. In this review, we discuss the pathogenesis of the diabetic infarcted heart and the potential of stem cell therapy to repair and regenerate.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 20559720 PMCID： PMC3072799 DOI： 10.1007/s10741-010-9172-8

Source DB: PubMed Journal: Heart Fail Rev ISSN： 1382-4147 Impact factor: 4.214

83 in total

1. Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats.

Authors: Jiang-Yong Min; Yinke Yang; Kimber L Converso; Lixin Liu; Qin Huang; James P Morgan; Yong-Fu Xiao
Journal: J Appl Physiol (1985) Date: 2002-01

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Authors: M Brownlee
Journal: Nature Date: 2001-12-13 Impact factor: 49.962

Review 3. Heart failure, redox alterations, and endothelial dysfunction.

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Journal: Hypertension Date: 2001-12-01 Impact factor: 10.190

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Authors: Lu Cai; Wei Li; Guangwu Wang; Luping Guo; Youchun Jiang; Y James Kang
Journal: Diabetes Date: 2002-06 Impact factor: 9.461

Review 5. Oxidative stress and apoptosis in heart dysfunction.

Authors: Dinender Kumar; Huiquan Lou; Pawan K Singal
Journal: Herz Date: 2002-11 Impact factor: 1.443

6. Myocardial infarction and prevalence of diabetes mellitus. Is increased casual blood glucose at admission a reliable criterion for the diagnosis of diabetes?

Authors: I Lönnberg; C Berne; G Nilsson; J Leppert
Journal: Eur Heart J Date: 2001-07 Impact factor: 29.983

7. The newly inbred cohen diabetic rat: a nonobese normolipidemic genetic model of diet-induced type 2 diabetes expressing sex differences.

Authors: S Weksler-Zangen; C Yagil; D H Zangen; A Ornoy; H J Jacob; Y Yagil
Journal: Diabetes Date: 2001-11 Impact factor: 9.461

Review 8. Glucose and reactive oxygen species.

Authors: Dominique Bonnefont-Rousselot
Journal: Curr Opin Clin Nutr Metab Care Date: 2002-09 Impact factor: 4.294

Review 9. Vascular function, insulin resistance and fatty acids.

Authors: H O Steinberg; A D Baron
Journal: Diabetologia Date: 2002-04-04 Impact factor: 10.122

10. Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells.

Authors: Massimo Federici; Rossella Menghini; Alessandro Mauriello; Marta Letizia Hribal; Francesca Ferrelli; Davide Lauro; Paolo Sbraccia; Luigi Giusto Spagnoli; Giorgio Sesti; Renato Lauro
Journal: Circulation Date: 2002-07-23 Impact factor: 29.690

9 in total

Review 1. Diabetes-associated macrovascular complications: cell-based therapy a new tool?

Authors: Maddalena Gili; Alberto Orsello; Sara Gallo; Maria Felice Brizzi
Journal: Endocrine Date: 2013-03-30 Impact factor: 3.633

2. Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts.

Authors: Heng Zeng; Lanfang Li; Jian-Xiong Chen
Journal: PLoS One Date: 2012-04-27 Impact factor: 3.240

Review 3. Cardiac regeneration and diabetes.

Authors: Lu Cai; Bradley B Keller
Journal: Regen Med Res Date: 2014-01-03

4. Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart.

Authors: Dinender Singla; Jing Wang
Journal: Oxid Med Cell Longev Date: 2015-11-22 Impact factor: 6.543

5. Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart.

Authors: Curtis C Hughey; Lianli Ma; Freyja D James; Deanna P Bracy; Zhizhang Wang; David H Wasserman; Jeffrey N Rottman; Dustin S Hittel; Jane Shearer
Journal: Cardiovasc Diabetol Date: 2013-09-04 Impact factor: 9.951

9. MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro.

Authors: Santosh K Yadav; Tyler N Kambis; Sumit Kar; Song Y Park; Paras K Mishra
Journal: Cell Death Dis Date: 2020-03-13 Impact factor: 8.469