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Literature DB >> 20559540

Mutational Analysis of ASPP1 and ASPP2 Genes, a p53-related Gene, in Gastric and Cololorectal Cancers with Microsatellite Instability.

Sang Wook Park¹, Chang Hyeok An, Sung Soo Kim, Nam Jin Yoo, Sug Hyung Lee.

Abstract

Entities: Disease Gene

Year: 2010 PMID： 20559540 PMCID： PMC2886944 DOI： 10.5009/gnl.2010.4.2.292

Source DB: PubMed Journal: Gut Liver ISSN： 1976-2283 Impact factor: 4.519

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6 in total

1. Surfing the p53 network.

Authors: B Vogelstein; D Lane; A J Levine
Journal: Nature Date: 2000-11-16 Impact factor: 49.962

2. ASPP proteins specifically stimulate the apoptotic function of p53.

Authors: Y Samuels-Lev; D J O'Connor; D Bergamaschi; G Trigiante; J K Hsieh; S Zhong; I Campargue; L Naumovski; T Crook; X Lu
Journal: Mol Cell Date: 2001-10 Impact factor: 17.970

3. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer.

Authors: S H Lee; M S Shin; W S Park; S Y Kim; H S Kim; J Y Han; G S Park; S M Dong; J H Pi; C S Kim; S H Kim; J Y Lee; N J Yoo
Journal: Oncogene Date: 1999-06-24 Impact factor: 9.867

Review 4. Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics.

Authors: Kohzoh Imai; Hiroyuki Yamamoto
Journal: Carcinogenesis Date: 2007-10-17 Impact factor: 4.944

5. Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.

Authors: Kerstin M Kampa; Jared D Acoba; Dexi Chen; Joel Gay; Hunjoo Lee; Kelly Beemer; Emerson Padiernos; Nataya Boonmark; Zhiyi Zhu; Alice C Fan; Alexis S Bailey; William H Fleming; Christopher Corless; Dean W Felsher; Louie Naumovski; Charles D Lopez
Journal: Proc Natl Acad Sci U S A Date: 2009-02-26 Impact factor: 11.205

6. Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.

Authors: Seema Patel; Roger George; Flavia Autore; Franca Fraternali; John E Ladbury; Penka V Nikolova
Journal: Nucleic Acids Res Date: 2008-08-02 Impact factor: 16.971

6 in total

4 in total

Mutational Analysis of ASPP1 and ASPP2 Genes, a p53-related Gene, in Gastric and Cololorectal Cancers with Microsatellite Instability.

1. Surfing the p53 network.

2. ASPP proteins specifically stimulate the apoptotic function of p53.

3. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer.

Review 4. Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics.

5. Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.

6. Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.

1. An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.

2. ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer.

3. Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

Review 4. Epithelial cell polarity: a major gatekeeper against cancer?