Literature DB >> 20557269

Emerging drugs for complicated skin and skin-structure infections.

Natalia Mendoza1, Stephen K Tyring.   

Abstract

UNLABELLED: IMPORTANCE OF THE FILED: With the worldwide surge of MRSA, skin and skin-structure infection (SSTI) treatment has become a challenge for physicians. Cultures and antibiotic susceptibility tests for SSTIs are the rule due to the implication in morbidity and mortality rates associated with MRSA infections. The need for new antibiotics is evident and the effort to decrease antibiotic resistance is a world priority. AREAS COVERED IN THIS REVIEW: This manuscript accesses the actual treatments and the developing of antibiotics for MRSA SSTIs. WHAT THE READER WILL GAIN: This is a review of the data on the available and emerging treatments for MRSA SSTIs. TAKE HOME MESSAGE: There is an unmet medical need for new antibiotics in the new millennium. As physicians, we must assure all appropriate procedures are completed in order to reduce the bacterial resistance, especially for MRSA.

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Year:  2010        PMID: 20557269     DOI: 10.1517/14728214.2010.497486

Source DB:  PubMed          Journal:  Expert Opin Emerg Drugs        ISSN: 1472-8214            Impact factor:   4.191


  6 in total

1.  Antimicrobial endotoxin-neutralizing peptides promote keratinocyte migration via P2X7 receptor activation and accelerate wound healing in vivo.

Authors:  Anja Pfalzgraff; Sergio Bárcena-Varela; Lena Heinbockel; Thomas Gutsmann; Klaus Brandenburg; Guillermo Martinez-de-Tejada; Günther Weindl
Journal:  Br J Pharmacol       Date:  2018-07-20       Impact factor: 8.739

2.  Bacteriocin isolated from the natural inhabitant of Allium cepa against Staphylococcus aureus.

Authors:  Ramita Taggar; Manoj Jangra; Akanksha Dwivedi; Kanika Bansal; Prabhu B Patil; Mani Shankar Bhattacharyya; Hemraj Nandanwar; Debendra K Sahoo
Journal:  World J Microbiol Biotechnol       Date:  2021-01-11       Impact factor: 3.312

3.  Ceftaroline in complicated skin and skin-structure infections.

Authors:  Paul O Hernandez; Sergio Lema; Stephen K Tyring; Natalia Mendoza
Journal:  Infect Drug Resist       Date:  2012-01-19       Impact factor: 4.003

Review 4.  Interplay between ESKAPE Pathogens and Immunity in Skin Infections: An Overview of the Major Determinants of Virulence and Antibiotic Resistance.

Authors:  Gustavo Henrique Rodrigues Vale de Macedo; Gabrielle Damasceno Evangelista Costa; Elane Rodrigues Oliveira; Glauciane Viera Damasceno; Juliana Silva Pereira Mendonça; Lucas Dos Santos Silva; Vitor Lopes Chagas; José Manuel Noguera Bazán; Amanda Silva Dos Santos Aliança; Rita de Cássia Mendonça de Miranda; Adrielle Zagmignan; Andrea de Souza Monteiro; Luís Cláudio Nascimento da Silva
Journal:  Pathogens       Date:  2021-02-02

5.  Improving antibiotic activity against wound pathogens with manuka honey in vitro.

Authors:  Rowena Jenkins; Rose Cooper
Journal:  PLoS One       Date:  2012-09-26       Impact factor: 3.240

Review 6.  Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds.

Authors:  Anja Pfalzgraff; Klaus Brandenburg; Günther Weindl
Journal:  Front Pharmacol       Date:  2018-03-28       Impact factor: 5.810

  6 in total

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