Literature DB >> 20556849

Principal manifolds and graphs in practice: from molecular biology to dynamical systems.

Alexander N Gorban1, Andrei Zinovyev.   

Abstract

We present several applications of non-linear data modeling, using principal manifolds and principal graphs constructed using the metaphor of elasticity (elastic principal graph approach). These approaches are generalizations of the Kohonen's self-organizing maps, a class of artificial neural networks. On several examples we show advantages of using non-linear objects for data approximation in comparison to the linear ones. We propose four numerical criteria for comparing linear and non-linear mappings of datasets into the spaces of lower dimension. The examples are taken from comparative political science, from analysis of high-throughput data in molecular biology, from analysis of dynamical systems.

Mesh:

Year:  2010        PMID: 20556849     DOI: 10.1142/S0129065710002383

Source DB:  PubMed          Journal:  Int J Neural Syst        ISSN: 0129-0657            Impact factor:   5.866


  14 in total

Review 1.  Blessing of dimensionality: mathematical foundations of the statistical physics of data.

Authors:  A N Gorban; I Y Tyukin
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2018-04-28       Impact factor: 4.226

2.  Trajectories, bifurcations, and pseudo-time in large clinical datasets: applications to myocardial infarction and diabetes data.

Authors:  Sergey E Golovenkin; Jonathan Bac; Alexander Chervov; Evgeny M Mirkes; Yuliya V Orlova; Emmanuel Barillot; Alexander N Gorban; Andrei Zinovyev
Journal:  Gigascience       Date:  2020-11-25       Impact factor: 6.524

3.  Fractional Norms and Quasinorms Do Not Help to Overcome the Curse of Dimensionality.

Authors:  Evgeny M Mirkes; Jeza Allohibi; Alexander Gorban
Journal:  Entropy (Basel)       Date:  2020-09-30       Impact factor: 2.524

4.  Prototyping and Simulation of Robot Group Intelligence using Kohonen Networks.

Authors:  Zhijun Wang; Reza Mirdamadi; Qing Wang
Journal:  IOSR J Comput Eng       Date:  2016 Sep-Oct

5.  Principal Graph and Structure Learning Based on Reversed Graph Embedding.

Authors:  Ivor W Tsang
Journal:  IEEE Trans Pattern Anal Mach Intell       Date:  2016-12-05       Impact factor: 6.226

6.  DeDaL: Cytoscape 3 app for producing and morphing data-driven and structure-driven network layouts.

Authors:  Urszula Czerwinska; Laurence Calzone; Emmanuel Barillot; Andrei Zinovyev
Journal:  BMC Syst Biol       Date:  2015-08-14

7.  Classification of gene signatures for their information value and functional redundancy.

Authors:  Laura Cantini; Laurence Calzone; Loredana Martignetti; Mattias Rydenfelt; Nils Blüthgen; Emmanuel Barillot; Andrei Zinovyev
Journal:  NPJ Syst Biol Appl       Date:  2017-12-19

8.  Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.

Authors:  Huidong Chen; Luca Albergante; Jonathan Y Hsu; Caleb A Lareau; Giosuè Lo Bosco; Jihong Guan; Shuigeng Zhou; Alexander N Gorban; Daniel E Bauer; Martin J Aryee; David M Langenau; Andrei Zinovyev; Jason D Buenrostro; Guo-Cheng Yuan; Luca Pinello
Journal:  Nat Commun       Date:  2019-04-23       Impact factor: 14.919

9.  Combination of the Manifold Dimensionality Reduction Methods with Least Squares Support vector machines for Classifying the Species of Sorghum Seeds.

Authors:  Y M Chen; P Lin; J Q He; Y He; X L Li
Journal:  Sci Rep       Date:  2016-01-28       Impact factor: 4.379

10.  Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.

Authors:  David P A Cohen; Loredana Martignetti; Sylvie Robine; Emmanuel Barillot; Andrei Zinovyev; Laurence Calzone
Journal:  PLoS Comput Biol       Date:  2015-11-03       Impact factor: 4.475

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