Daniel Maoz1, Eran Sharon, Yakov Chen, Franklin Grief. 1. Department of Surgery A, Rabin Medical Center, Beilinson Campus, Petach Tikva, and Sackler Tel Aviv University, Tel Aviv, Israel.
Abstract
BACKGROUND: Spontaneous hepatic rupture is a rare clinical event associated with various pathologies of the liver. Most series to date reported the incidence and characteristics of a single etiology. METHODS: Data were collected for all patients admitted with spontaneous hepatic rupture from 1995 to 2007. RESULTS: Ten patients met the study criteria. Hepatocellular adenoma was the cause of the rupture in six female patients, in their second to fourth decade. In the remaining patients, the ruptures were because of hepatocellular carcinoma in two, metastatic gastrointestinal stromal tumor in one, and HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) in one. Nine out of 10 patients were treated surgically. CONCLUSION: Spontaneous hepatic rupture requires a high index of suspicion for a correct and timely diagnosis. Outcome is potentially grave and greatly depends on the underlying condition.
BACKGROUND:Spontaneous hepatic rupture is a rare clinical event associated with various pathologies of the liver. Most series to date reported the incidence and characteristics of a single etiology. METHODS: Data were collected for all patients admitted with spontaneous hepatic rupture from 1995 to 2007. RESULTS: Ten patients met the study criteria. Hepatocellular adenoma was the cause of the rupture in six female patients, in their second to fourth decade. In the remaining patients, the ruptures were because of hepatocellular carcinoma in two, metastatic gastrointestinal stromal tumor in one, and HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) in one. Nine out of 10 patients were treated surgically. CONCLUSION:Spontaneous hepatic rupture requires a high index of suspicion for a correct and timely diagnosis. Outcome is potentially grave and greatly depends on the underlying condition.
Authors: Jae Young Jang; Moon Young Kim; Soung Won Jeong; Tae Yeob Kim; Seung Up Kim; Sae Hwan Lee; Ki Tae Suk; Soo Young Park; Hyun Young Woo; Sang Gyune Kim; Jeong Heo; Soon Koo Baik; Hong Soo Kim; Won Young Tak Journal: Clin Mol Hepatol Date: 2013-03-25