Literature DB >> 20552486

Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities.

Guang-Yu Yang1, Yin-Ke Li, Rui-Rui Wang, Wei-Lie Xiao, Liu-Meng Yang, Jian-Xin Pu, Yong-Tang Zheng, Han-Dong Sun.   

Abstract

Three new dibenzocyclooctadiene lignans, wilsonilignans A-C (1-3), together with nine known ones, were isolated from the fruits of Schisandra wilsoniana. The structures of 1-3 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-3 were also evaluated for their anti-HIV-1 activities and showed bioactivity with EC(50) values of 3.26, 6.18, and 2.87 microg/ml, respectively.

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Year:  2010        PMID： 20552486     DOI： 10.1080/10286020.2010.489823

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  5 in total

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Review 2.  Plant-derived lignans as potential antiviral agents: a systematic review.

Authors:  Xin-Ya Xu; Dong-Ying Wang; Yi-Ping Li; Stephen T Deyrup; Hong-Jie Zhang
Journal:  Phytochem Rev       Date:  2021-05-31       Impact factor: 7.741

3.  Dietary pulp from Fructus Schisandra Chinensis supplementation reduces serum/hepatic lipid and hepatic glucose levels in mice fed a normal or high cholesterol/bile salt diet.

Authors:  Nan Sun; Si-Yuan Pan; Yi Zhang; Xiao-Yan Wang; Pei-Li Zhu; Zhu-Sheng Chu; Zhi-Ling Yu; Shu-Feng Zhou; Kam-Ming Ko
Journal:  Lipids Health Dis       Date:  2014-03-12       Impact factor: 3.876

Review 4.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923

5.  Neglschisandrins E-F: two new lignans and related cytotoxic lignans from Schisandra neglecta.

Authors:  Min Chen; Xiumei Xu; Bing Xu; Panpan Yang; Zhihua Liao; Susan L Morris-Natschke; Kuo-Hsiung Lee; Daofeng Chen
Journal:  Molecules       Date:  2013-02-19       Impact factor: 4.411
  5 in total

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