Literature DB >> 20552239

Wound botulism in drug users: a still underestimated diagnosis.

C Rodolico1, E Barca, L Fenicia, F Anniballi, A U Sinardi, P Girlanda.   

Abstract

Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset of slurred speech and dysphagia. The most considerable finding of electrophysiological study was the reduction in amplitude of compound muscle action potential which should be considered a useful initial electrodiagnostic sign in the clinical context of botulism. Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications.

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Year:  2010        PMID: 20552239     DOI: 10.1007/s10072-010-0350-1

Source DB:  PubMed          Journal:  Neurol Sci        ISSN: 1590-1874            Impact factor:   3.307


  8 in total

Review 1.  Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission.

Authors:  Frédéric A Meunier; Giampietro Schiavo; Jordi Molgó
Journal:  J Physiol Paris       Date:  2002 Jan-Mar

2.  Wound botulism in the UK and Ireland.

Authors:  Moira M Brett; Gill Hallas; Obioma Mpamugo
Journal:  J Med Microbiol       Date:  2004-06       Impact factor: 2.472

3.  Electrophysiological diagnosis and patterns of response to treatment of botulism with neuromuscular respiratory failure.

Authors:  Subsai Kongsaengdao; Kanoksri Samintarapanya; Siwarit Rusmeechan; Pasiri Sithinamsuwan; Surat Tanprawate
Journal:  Muscle Nerve       Date:  2009-08       Impact factor: 3.217

4.  Cardiovascular-reflex testing and single-fiber electromyography in botulism. A longitudinal study.

Authors:  G Vita; P Girlanda; R M Puglisi; L Marabello; C Messina
Journal:  Arch Neurol       Date:  1987-02

Review 5.  Wound botulism in injectors of drugs: upsurge in cases in England during 2004.

Authors:  D Akbulut; J Dennis; M Gent; K A Grant; V Hope; C Ohai; J McLauchlin; V Mithani; O Mpamugo; F Ncube; L de Souza-Thomas
Journal:  Euro Surveill       Date:  2005-09

6.  Wound botulism in California, 1951-1998: recent epidemic in heroin injectors.

Authors:  S B Werner; D Passaro; J McGee; R Schechter; D J Vugia
Journal:  Clin Infect Dis       Date:  2000-10-25       Impact factor: 9.079

7.  Outbreak of wound botulism in injecting drug users.

Authors:  M Schroeter; K Alpers; U Van Treeck; C Frank; N Rosenkoetter; R Schaumann
Journal:  Epidemiol Infect       Date:  2009-04-07       Impact factor: 2.451

8.  Botulism in injecting drug users, Dublin, Ireland, November-December 2008.

Authors:  J Barry; M Ward; S Cotter; J Macdiarmada; M Hannan; B Sweeney; K A Grant; P McKeown
Journal:  Euro Surveill       Date:  2009-01-08
  8 in total
  2 in total

1.  Emerging and Underrecognized Complications of Illicit Drug Use.

Authors:  Alysse G Wurcel; Elisabeth A Merchant; Roger P Clark; David R Stone
Journal:  Clin Infect Dis       Date:  2015-08-12       Impact factor: 9.079

2.  Draft Genome Sequence of Clostridium botulinum B2 450 Strain from Wound Botulism in a Drug User in Italy.

Authors:  Silvia Fillo; Francesco Giordani; Anna Anselmo; Antonella Fortunato; Anna Maria Palozzi; Riccardo De Santis; Andrea Ciammaruconi; Ferdinando Spagnolo; Fabrizio Anniballi; Alfonsina Fiore; Bruna Auricchio; Dario De Medici; Florigio Lista
Journal:  Genome Announc       Date:  2015-04-02
  2 in total

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