Literature DB >> 20550959

Chemical constituents from Delphinium chrysotrichum and their biological activity.

Yang-Qing He1, Zhan-Ying Ma, Xiao-Mei Wei, Bao-Zhong Du, Zhan-Xin Jing, Bing-Hua Yao, Li-Ming Gao.   

Abstract

A new diterpene alkaloid named delphatisine C (1) has been isolated from aerial parts of Delphinium chrysotrichum along with three known norditerpenoid alkaloids delpheline (2), delbrunine (3), and delectinine (4). Their structures were characterized on the basis of their spectral data. All of them were determined by SRB assay for their cytotoxicity, and compound (1) showed significant cytotoxic activities (IC(50)=2.36 μmol/L) against the A549 cell line.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20550959     DOI: 10.1016/j.fitote.2010.06.008

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  3 in total

Review 1.  Two decades of advances in diterpenoid alkaloids with cytotoxicity activities.

Authors:  Xiaoxia Liang; Yingying Gao; Shangxian Luan
Journal:  RSC Adv       Date:  2018-07-02       Impact factor: 4.036

2.  Anticancer Activity of Delphinium semibarbatum Alkaloid Fractions against LNCaP, and DU 145 Human Prostate Cancer Cells through the Intrinsic Apoptotic Pathway.

Authors:  Mohammadreza Lotfaliani; Mustafa Ghanadian; Seyed Abdulmajid Ayatollahi; Mahmoud Aghaei; Farzad Kobarfard
Journal:  Iran J Pharm Res       Date:  2021       Impact factor: 1.696

Review 3.  An overview of the chemical constituents from the genus Delphinium reported in the last four decades.

Authors:  Tianpeng Yin; Le Cai; Zhongtao Ding
Journal:  RSC Adv       Date:  2020-04-03       Impact factor: 4.036

  3 in total

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