Literature DB >> 20550955

Two new triterpenoids from the roots of Actinidia chinensis.

Yi-Xin Xu1, Zhao-Bao Xiang, Yong-Sheng Jin, Yang Shen, Hai-Sheng Chen.   

Abstract

Two new triterpenoids (1, 2), together with one flavonoid glycoside and thirteen known triterpenoids were isolated from the roots of Actinidia chinensis Planch (Actinidiaceae). The structures of the new constituents were elucidated as 12α-chloro-2α, 3β, 13β, 23-tetrahydroxyolean-28-oic acid-13-lactone (1), 2α, 3α, 19α, 23, 24-pentahydroxyurs-12-en-28-oic acid (2). Structure elucidation was accomplished by 1D, 2D NMR spectra (HMQC, HMBC, (1)H-(1)H COSY, TOCSY, and NOESY) and mass spectrometry (ESIMS). Moreover, two known triterpenoids showed positive cytotoxic activity against LOVO and HepG2 cell lines.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20550955     DOI: 10.1016/j.fitote.2010.06.007

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  4 in total

Review 1.  Actinidia chinensis Planch.: A Review of Chemistry and Pharmacology.

Authors:  Xirui He; Jiacheng Fang; Xufei Chen; Zefeng Zhao; Yongsheng Li; Yibing Meng; Linhong Huang
Journal:  Front Pharmacol       Date:  2019-10-30       Impact factor: 5.810

2.  Ethanol Extracted from Radix of Actinidia Chinensis Inhibits Human Colon Tumor Through Inhibiting Notch-signaling Pathway.

Authors:  Wanle Hu; Chenchen Wu; Chenchen Yuan; Minyuan Chen; Chun Jin; Chenguo Zheng
Journal:  J Cancer       Date:  2021-01-01       Impact factor: 4.207

3.  Inhibition to Epithelial-Mesenchymal Transition and Metastatic Potential In Colorectal Cancer Cell By Combination of Traditional Chinese Medicine Formulation Jiedu Sangen Decoction and PD-L1 Inhibitor.

Authors:  Feiyu Shan; Leitao Sun; Leyin Zhang; Kaibo Guo; Qingying Yan; Guan Feng; Ying Zhu; Minhe Shen; Shanming Ruan
Journal:  Integr Cancer Ther       Date:  2020 Jan-Dec       Impact factor: 3.279

4.  Secondary metabolites from two species of Tolpis and their biological activities.

Authors:  Jorge Triana; Mariana López; Francisco Javier Pérez; Milagros Rico; Aroa López; Francisco Estévez; María Teresa Marrero; Ignacio Brouard; Francisco León
Journal:  Molecules       Date:  2012-11-01       Impact factor: 4.411

  4 in total

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