| Literature DB >> 20550927 |
Abstract
The selectivity filter of potassium channels, the narrowest segment of the pore, permits only potassium ions to diffuse through the pore. Clarke et al. (2010) now present 11 structures of an inwardly rectifying potassium channel, providing evidence that the selectivity filter functions in channel gating and conformational changes in the cytoplasmic domains correlate with pore opening. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
Year: 2010 PMID： 20550927 DOI： 10.1016/j.cell.2010.05.038
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582