Literature DB >> 20550685

Duodenal enteroglucagonoma revealed by differential comparison of serum and tissue glucagon reactivity with Siemens' Double Glucagon Antibody and DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon: a case report.

Wesley B Vanderlan1, Ziying Zhang, Marwan S Abouljoud.   

Abstract

INTRODUCTION: This case report demonstrates that the differential immunohistochemical reactivities of Siemens' Double Antibody Glucagon compared to DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon allow for pathologic distinction of enteral versus pancreatic glucagonoma. CASE
PRESENTATION: A 64-year-old Caucasian man was diagnosed with a duodenal enteroglucagonoma following presentation with obstructive jaundice. He had a low serum glucagon level using Siemens' Double Antibody Glucagon, a clinical syndrome consistent with glucagon hypersecretion. A periampullary mass biopsy proved to be a neuroendocrine tumor, with positive immunohistochemical reactivity to DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon.
CONCLUSIONS: Differential comparison of the immunohistochemical reactivities of Siemens' Double Antibody Glucagon and DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon discerns enteroglucagon from pancreatic glucagon.

Entities:  

Year:  2010        PMID： 20550685      PMCID： PMC2896376          DOI： 10.1186/1752-1947-4-178

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN： 1752-1947


  10 in total

1.  Pancreatic glucagonoma as a rare cause of chronic obstructive pancreatitis.

Authors:  O Pech; T Lingenfelser; P Wünsch
Journal:  Gastrointest Endosc       Date:  2000-10       Impact factor: 9.427

Review 2.  Pancreatic endocrine tumors.

Authors:  John C Mansour; Herbert Chen
Journal:  J Surg Res       Date:  2004-07       Impact factor: 2.192

Review 3.  Neuroendocrine tumors.

Authors:  Orlo H Clark; Jaffer Ajani; Al B Benson; David Byrd; Gerard M Doherty; Paul F Engstrom; David S Ettinger; John F Gibbs; Martin J Heslin; Fouad Kandeel; Anne Kessinger; Matthew H Kulke; Larry Kvols; Albert A Nemcek; John A Olson; Thomas W Ratliff; Leonard Saltz; David E Schteingart; Manisha H Shah; Stephen Shibata
Journal:  J Natl Compr Canc Netw       Date:  2006-02       Impact factor: 11.908

Review 4.  Rare endocrine tumours of the GI tract.

Authors:  Gerard M Doherty
Journal:  Best Pract Res Clin Gastroenterol       Date:  2005-10       Impact factor: 3.043

Review 5.  Endocrine tumours of the pancreas.

Authors:  Kjell Oberg; Barbro Eriksson
Journal:  Best Pract Res Clin Gastroenterol       Date:  2005-10       Impact factor: 3.043

Review 6.  The glucagonoma syndrome: clinical features, diagnosis, and treatment.

Authors:  P W Stacpoole
Journal:  Endocr Rev       Date:  1981       Impact factor: 19.871

Review 7.  Enteroglucagon.

Authors:  J J Holst
Journal:  Annu Rev Physiol       Date:  1997       Impact factor: 19.318

8.  Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function.

Authors:  M H Gleeson; S R Bloom; J M Polak; K Henry; R H Dowling
Journal:  Gut       Date:  1971-10       Impact factor: 23.059

9.  Glucagonoma syndrome demonstrating giant duodenal villi.

Authors:  F M Stevens; R W Flanagan; D O'Gorman; K D Buchanan
Journal:  Gut       Date:  1984-07       Impact factor: 23.059

10.  Duodenal glucagonoma: a case report.

Authors:  V L Roggli; D M Judge; M H McGavran
Journal:  Hum Pathol       Date:  1979-05       Impact factor: 3.466
  10 in total
  2 in total

1.  Glucagonoma and the glucagonoma syndrome.

Authors:  Xujun Song; Suli Zheng; Gang Yang; Guangbing Xiong; Zhe Cao; Mengyu Feng; Taiping Zhang; Yupei Zhao
Journal:  Oncol Lett       Date:  2017-12-28       Impact factor: 2.967

Review 2.  Pancreatic neuroendocrine tumors: clinical features, diagnosis and medical treatment: advances.

Authors:  Tetsuhide Ito; Hisato Igarashi; Robert T Jensen
Journal:  Best Pract Res Clin Gastroenterol       Date:  2012-12       Impact factor: 3.043
  2 in total

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