Literature DB >> 20548980

Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: insights from baseline findings in the circumpolar Inuit health in transition cohort study.

Marie-Ludivine Chateau-Degat1, Eric Dewailly, Rabia Louchini, Emilie Counil, Martin Noël, Annie Ferland, Michel Lucas, Béatriz Valera, Jean-Marie Ekoé, Robert Ladouceur, S Déry, Grace Egeland.   

Abstract

BACKGROUND: The Inuit are commonly portrayed to be somehow protected from cardiovascular diseases (CVDs) through their traditional lifestyle and diet. However, actual sociocultural transition and related major, modifiable risk factors have scarcely been quantified in the Inuit population. Such knowledge is extremely valuable in terms of public health intervention.
METHODS: A total of 887 Inuit residents from Nunavik, Quebec, participated in a cohort study. The estimates presented were derived from anthropometric and biological measurements gathered at the time of recruitment and enhanced by information collected in the medical file of each participant. All estimates were corrected for a complex sampling strategy and bootstrapped to ensure the representativeness of the general Nunavik population.
RESULTS: Overall, 19% of Inuit had a disease of the circulatory system according to the International Statistical Classification of Diseases and Related Health Problems, 10th revision. Among all disorders, peripheral circulatory system disease was the most prevalent (9%). Prevalences of ischemic heart disease and cerebrovascular disease were of similar magnitude (2.5%). No significant difference in disease prevalence was noted between sexes. The major modifiable CVD risk factors were smoking (84%), obesity (49%) [corrected] (body mass index of greater than 30 kgm2) and elevated blood pressure (13085 mmHg or greater) (18%). Prevalences were globally higher among women.
CONCLUSION: The current belief that the Inuit are protected from CVD is seriously questioned by the results of the present study. Considering the extremely high prevalence of CVD risk factors, a population-based intervention reinforced for women is urgently needed to reduce their risk.

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Year:  2010        PMID: 20548980      PMCID: PMC2903990          DOI: 10.1016/s0828-282x(10)70398-6

Source DB:  PubMed          Journal:  Can J Cardiol        ISSN: 0828-282X            Impact factor:   5.223


  37 in total

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Authors:  R J Kuczmarski; K M Flegal
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2.  Plasma lipid and lipoprotein pattern in Greenlandic West-coast Eskimos.

Authors:  H O Bang; J Dyerberg; A B Nielsen
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3.  Diabetes mellitus in Eskimos after a decade.

Authors:  G J Mouratoff; E M Scott
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4.  Fish consumption and blood lipids in three ethnic groups of Québec (Canada).

Authors:  Eric Dewailly; Carole Blanchet; Suzanne Gingras; Simone Lemieux; Bruce John Holub
Journal:  Lipids       Date:  2003-04       Impact factor: 1.880

5.  Trends in risk factors for cardiovascular disease in Canada: temporal, socio-demographic and geographic factors.

Authors:  Douglas S Lee; Maria Chiu; Douglas G Manuel; Karen Tu; Xuesong Wang; Peter C Austin; Michelle Y Mattern; Tezeta F Mitiku; Lawrence W Svenson; Wayne Putnam; William M Flanagan; Jack V Tu
Journal:  CMAJ       Date:  2009-07-20       Impact factor: 8.262

6.  Are the circumpolar Inuit becoming obese?

Authors:  T K Young
Journal:  Am J Hum Biol       Date:  2007 Mar-Apr       Impact factor: 1.937

7.  Hypertension treatment and control in five European countries, Canada, and the United States.

Authors:  Katharina Wolf-Maier; Richard S Cooper; Holly Kramer; José R Banegas; Simona Giampaoli; Michel R Joffres; Neil Poulter; Paola Primatesta; Birgitta Stegmayr; Michael Thamm
Journal:  Hypertension       Date:  2003-11-24       Impact factor: 10.190

8.  Blood pressure among the Inuit (Eskimo) populations in the Arctic.

Authors:  Peter Bjerregaard; Eric Dewailly; T Kue Young; Carole Blanchet; Robert A Hegele; Sven E O Ebbesson; Patricia M Risica; Gert Mulvad
Journal:  Scand J Public Health       Date:  2003       Impact factor: 3.021

9.  Trans-polar-fat: all Inuit are not equal.

Authors:  Émilie Counil; Éric Dewailly; Peter Bjerregaard; Pierre Julien
Journal:  Br J Nutr       Date:  2008-10       Impact factor: 3.718

10.  Lower prevalence of impaired glucose tolerance and diabetes associated with daily seal oil or salmon consumption among Alaska Natives.

Authors:  A I Adler; E J Boyko; C D Schraer; N J Murphy
Journal:  Diabetes Care       Date:  1994-12       Impact factor: 19.112

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  18 in total

1.  Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007-2008.

Authors:  Grace M Egeland; Zhirong Cao; T Kue Young
Journal:  CMAJ       Date:  2011-05-09       Impact factor: 8.262

2.  Common low-density lipoprotein receptor p.G116S variant has a large effect on plasma low-density lipoprotein cholesterol in circumpolar inuit populations.

Authors:  Joseph B Dubé; Jian Wang; Henian Cao; Adam D McIntyre; Christopher T Johansen; Scarlett E Hopkins; Randa Stringer; Siyavash Hosseinzadeh; Brooke A Kennedy; Matthew R Ban; T Kue Young; Philip W Connelly; Eric Dewailly; Peter Bjerregaard; Bert B Boyer; Robert A Hegele
Journal:  Circ Cardiovasc Genet       Date:  2014-11-20

3.  Design and methods of the Adult Inuit Health Survey 2007-2008.

Authors:  Helga Saudny; Donna Leggee; Grace Egeland
Journal:  Int J Circumpolar Health       Date:  2012-11-16       Impact factor: 1.228

4.  Relation between methylmercury exposure and plasma paraoxonase activity in inuit adults from Nunavik.

Authors:  Pierre Ayotte; Antoine Carrier; Nathalie Ouellet; Véronique Boiteau; Belkacem Abdous; Elhadji Anassour Laouan Sidi; Marie-Ludivine Château-Degat; Éric Dewailly
Journal:  Environ Health Perspect       Date:  2011-05-04       Impact factor: 9.031

5.  Obesity and obesity-associated cardiometabolic risk factors in indigenous Nenets women from the rural Nenets Autonomous Area and Russian women from Arkhangelsk city.

Authors:  Natalia Petrenya; Magritt Brustad; Liliya Dobrodeeva; Fatima Bichkaeva; Gulnara Lutfalieva; Marie Cooper; Jon Øyvind Odland
Journal:  Int J Circumpolar Health       Date:  2014-07-24       Impact factor: 1.228

6.  Prevalence of the use of antihypertensive medications in Greenland: a study of quality of care amongst patients treated with antihypertensive drugs.

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Journal:  Int J Circumpolar Health       Date:  2012-06-13       Impact factor: 1.228

7.  Association between socioeconomic status and overweight and obesity among Inuit adults: International Polar Year Inuit Health Survey, 2007-2008.

Authors:  Natalia Zienczuk; Grace M Egeland
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8.  Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population.

Authors:  Iwona Rudkowska; Catherine Ouellette; Eric Dewailly; Robert A Hegele; Véronique Boiteau; Ariane Dubé-Linteau; Belkacem Abdous; Françoise Proust; Yves Giguère; Pierre Julien; Marie-Ludivine Château-Degat; Marie-Claude Vohl
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9.  Population-based study of high plasma C-reactive protein concentrations among the Inuit of Nunavik.

Authors:  Marie-Eve Labonté; Eric Dewailly; Marie-Ludivine Chateau-Degat; Patrick Couture; Benoît Lamarche
Journal:  Int J Circumpolar Health       Date:  2012-10-17       Impact factor: 1.228

10.  Tobacco use prevalence--disentangling associations between Alaska Native race, low socio-economic status and rural disparities.

Authors:  Julia A Dilley; Erin Peterson; Matthew Bobo; Kathryn E Pickle; Kristen Rohde
Journal:  Int J Circumpolar Health       Date:  2013-08-05       Impact factor: 1.228

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