Literature DB >> 2054881

Cytotoxic acetylenes from Panax quinquefolium.

Y Fujimoto1, M Satoh, N Takeuchi, M Kirisawa.   

Abstract

Three new cytotoxic polyacetylenes, PQ-1 (1), PQ-2 (2) and PQ-3 (3), have been isolated from Panax quinquefolium. The structures of these acetylenes were determined by analyses of their 1H-1H and 1H-13C COSY spectra. All these compounds exhibited strong cytotoxic activities against leukemia cells (L 1210) in tissue culture.

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Year:  1991        PMID: 2054881     DOI: 10.1248/cpb.39.521

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  8 in total

1.  Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.

Authors:  Shixin Deng; Shao-Nong Chen; Ping Yao; Dejan Nikolic; Richard B van Breemen; Judy L Bolton; Harry H S Fong; Norman R Farnsworth; Guido F Pauli
Journal:  J Nat Prod       Date:  2006-04       Impact factor: 4.050

2.  Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds.

Authors:  Lars P Christensen; Martin Jensen
Journal:  J Nat Med       Date:  2008-12-16       Impact factor: 2.343

Review 3.  Anticancer activity of natural and synthetic acetylenic lipids.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-10       Impact factor: 1.880

4.  pS2 expression induced by American ginseng in MCF-7 breast cancer cells.

Authors:  R B Duda; B Taback; B Kessel; D D Dooley; H Yang; J Marchiori; B M Slomovic; J G Alvarez
Journal:  Ann Surg Oncol       Date:  1996-11       Impact factor: 5.344

5.  Anti-TB polyynes from the roots of Angelica sinensis.

Authors:  Shixin Deng; Yuehong Wang; Taichi Inui; Shao-Nong Chen; Norman R Farnsworth; Sanghyun Cho; Scott G Franzblau; Guido F Pauli
Journal:  Phytother Res       Date:  2008-07       Impact factor: 5.878

6.  Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation.

Authors:  Stig Purup; Eric Larsen; Lars P Christensen
Journal:  J Agric Food Chem       Date:  2009-09-23       Impact factor: 5.279

7.  Polyacetylenes from sardinian Oenanthe fistulosa: a molecular clue to risus sardonicus.

Authors:  Giovanni Appendino; Federica Pollastro; Luisella Verotta; Mauro Ballero; Adriana Romano; Paulina Wyrembek; Katarzyna Szczuraszek; Jerzy W Mozrzymas; Orazio Taglialatela-Scafati
Journal:  J Nat Prod       Date:  2009-05-22       Impact factor: 4.050

Review 8.  Bioactive C17 and C18 Acetylenic Oxylipins from Terrestrial Plants as Potential Lead Compounds for Anticancer Drug Development.

Authors:  Lars Porskjær Christensen
Journal:  Molecules       Date:  2020-05-31       Impact factor: 4.411

  8 in total

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