Literature DB >> 2054865

Analgesic principles from Aralia cordata Thunb.

E Okuyama1, S Nishimura, M Yamazaki.   

Abstract

The analgesic principles from Aralia cordata Thunb, were identified with (ent)-kaur-16-en-19-oic acid (KA) and (ent)-pimara-8(14),15-dien-19-oic acid (PA), respectively. Both compounds were significantly effective regarding analgesics, hypothermia, duration of pentobarbital-induced anesthesia, and depression of locomotor activity enhanced by methamphetamine at doses of 300 mg/kg (KA) and 500 mg/kg (PA) by oral administration.

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Year:  1991        PMID： 2054865     DOI： 10.1248/cpb.39.405

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  6 in total

1.  Genetic analysis of Aralia cordata Thunb by RAPD.

Authors:  Fan Qu; Jue Zhou; Zhou Zhou; Huiyu Li; Elizabeth Burrows
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-10-25

2.  Aralia cordata Thunb. as a Source of Bioactive Compounds: Phytochemical Composition and Antioxidant Activity.

Authors:  Viktorija Puzerytė; Pranas Viškelis; Aistė Balčiūnaitienė; Paulina Štreimikytė; Jonas Viškelis; Dalia Urbonavičienė
Journal:  Plants (Basel)       Date:  2022-06-28

3.  Pimaradienoic Acid Inhibits Carrageenan-Induced Inflammatory Leukocyte Recruitment and Edema in Mice: Inhibition of Oxidative Stress, Nitric Oxide and Cytokine Production.

Authors:  Sandra S Mizokami; Miriam S N Hohmann; Larissa Staurengo-Ferrari; Thacyana T Carvalho; Ana C Zarpelon; Maria I Possebon; Anderson R de Souza; Rodrigo C S Veneziani; Nilton S Arakawa; Rubia Casagrande; Waldiceu A Verri
Journal:  PLoS One       Date:  2016-02-19       Impact factor: 3.240

4.  Continentalic Acid Rather Than Kaurenoic Acid Is Responsible for the Anti-Arthritic Activity of Manchurian Spikenard In Vitro and In Vivo.

Authors:  Riwon Hong; Kyoung Soo Kim; Gwang Muk Choi; Mijung Yeom; Bombi Lee; Sanghyun Lee; Ki Sung Kang; Hyang Sook Lee; Hi-Joon Park; Dae-Hyun Hahm
Journal:  Int J Mol Sci       Date:  2019-11-04       Impact factor: 5.923

5.  In vitro Cytotoxicity of Methanol Extract from Aerial Parts of Aralia cachemirica and Purified Continentalic Acid.

Authors:  B S Arora; Ekta Sharma; S K Agrawal; Madhunika Agrawal
Journal:  Indian J Pharm Sci       Date:  2015 Nov-Dec       Impact factor: 0.975

6.  Aralia continentalis kitagawa Extract Attenuates the Fatigue Induced by Exhaustive Exercise through Inhibition of Oxidative Stress.

Authors:  Dong Kwon Yang; Sei-Jin Lee; Gareeballah Osman Adam; Shang-Jin Kim
Journal:  Antioxidants (Basel)       Date:  2020-05-04
  6 in total

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