Literature DB >> 20548221

Posterior pharyngeal augmentation in the treatment of velopharyngeal insufficiency: a 40-year experience.

Michael Lypka1, Rafi Bidros, Murtaza Rizvi, Mark Gaon, Adam Rubenstein, Donna Fox, Ernest Cronin.   

Abstract

BACKGROUND: Velopharyngeal insufficiency (VPI) remains a common problem in the care of patients with cleft palate and other related conditions. It may be successfully corrected with augmentation of the posterior pharynx. The purpose of this study was to review the experience and results of posterior pharyngeal augmentation over a 40-year period at one cleft center in the United States.
METHODS: All patients from 1968 to 2008 who underwent posterior pharyngeal augmentation for the treatment of VPI were reviewed retrospectively. Diagnosis, age at the time of operation, type of implant used, duration of follow-up, speech performance both pre- and postoperatively, and complications were analyzed. Speech performance preoperatively was assessed by video fluoroscopy and/or nasoendoscopy. Resonance was assessed by both the surgeon and speech pathologist using a 4 point grading scale.
RESULTS: One hundred eleven patients underwent posterior pharyngeal augmentation. Thirteen patients required removal of the implant because of extrusion (n = 12) or postoperative sleep apnea (n = 1). Five patients with failed implants at the primary operation had successful replacement at a second operation, resulting in a retained implant success rate of 93%. Of the 103 patients who were successfully augmented, 15 were lost to follow-up, leaving 88 patients with full postoperative speech evaluations. Of the 88 patients evaluated, 64 exhibited normal or near normal speech (73%), 22 patients had mildly nasal speech (25%), and 2 patients (2%) were not improved. Highest extrusion rates were seen for smooth surface silicone and rolled gortex implants.
CONCLUSION: Augmentation of the posterior pharyngeal wall is a safe and effective treatment for patients with VPI. Implants are well tolerated and speech is substantially improved.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20548221     DOI: 10.1097/SAP.0b013e3181c1fec6

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  4 in total

1.  Posterior pharyngeal wall augmentation in post-adenoidectomy velopharyngeal insufficiency.

Authors:  Ayman Amer; Anas Magdy Saqr; Ahmed Mohamed Zayed; Mohamed El-Kotb; Ahmed Elsobki
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-05-09       Impact factor: 3.236

2.  Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.

Authors:  Ping Kong; Silvia E Racedo; Stephania Macchiarulo; Zunju Hu; Courtney Carpenter; Tingwei Guo; Tao Wang; Deyou Zheng; Bernice E Morrow
Journal:  Hum Mol Genet       Date:  2014-04-04       Impact factor: 6.150

3.  Autologous fat injection to face and neck: from soft tissue augmentation to regenerative medicine.

Authors:  R F Mazzola; G Cantarella; S Torretta; A Sbarbati; L Lazzari; L Pignataro
Journal:  Acta Otorhinolaryngol Ital       Date:  2011-04       Impact factor: 2.124

4.  Assessment of outcomes and complications of posterior pharyngeal wall augmentation with dermal fat graft in patients with Velopharyngeal Insufficiency (VPI) after primary cleft palate repair: A pilot study.

Authors:  Hossein Abdali; Mohammad Yaribakht
Journal:  JPRAS Open       Date:  2018-10-26
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.