Literature DB >> 20547517

Lead and children: clinical management for family physicians.

Alan R Abelsohn1, Margaret Sanborn.   

Abstract

OBJECTIVE: To provide family physicians with a practical, evidence-based approach to screening for and preventing children's exposure to lead. SOURCES OF INFORMATION: MEDLINE was searched using terms relevant to lead exposure and poisoning. We reviewed English-language articles published in 2003 to 2008. Most cited studies provide level 2 or 3 evidence. MAIN MESSAGE: Lead is a developmental neurotoxin. Children are most commonly exposed and they are most vulnerable. Lead exposure has been associated with many cognitive and motor deficits, as well as distractibility and other characteristics of attention deficit hyperactivity disorder. Although children's blood lead levels have declined considerably over the past 3 decades with removal of lead from gasoline and paint, children can still be exposed to lead from lead paint in older homes, toys, and other sources. Because post-exposure treatment cannot reverse the cognitive effects of lead exposure, preventing lead exposure is essential.
CONCLUSION: Family physicians have an important role in screening for children at high risk of lead exposure, and in educating families to prevent the exposure of children to lead.

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Year:  2010        PMID: 20547517      PMCID: PMC2902938     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  36 in total

1.  Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter.

Authors:  Richard L Canfield; Charles R Henderson; Deborah A Cory-Slechta; Christopher Cox; Todd A Jusko; Bruce P Lanphear
Journal:  N Engl J Med       Date:  2003-04-17       Impact factor: 91.245

2.  Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescents.

Authors:  B P Lanphear; K Dietrich; P Auinger; C Cox
Journal:  Public Health Rep       Date:  2000 Nov-Dec       Impact factor: 2.792

3.  Effect of smelter emission reductions on children's blood lead levels.

Authors:  Steven R Hilts
Journal:  Sci Total Environ       Date:  2003-02-15       Impact factor: 7.963

Review 4.  Identifying and managing adverse environmental health effects: 1. Taking an exposure history.

Authors:  Lynn Marshall; Erica Weir; Alan Abelsohn; Margaret D Sanborn
Journal:  CMAJ       Date:  2002-04-16       Impact factor: 8.262

5.  Lead intoxication in children with pervasive developmental disorders.

Authors:  M Shannon; J W Graef
Journal:  J Toxicol Clin Toxicol       Date:  1996

6.  Absorption and retention of lead by infants.

Authors:  E E Ziegler; B B Edwards; R L Jensen; K R Mahaffey; S J Fomon
Journal:  Pediatr Res       Date:  1978-01       Impact factor: 3.756

7.  Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial.

Authors:  Mauricio Hernandez-Avila; Teresa Gonzalez-Cossio; Juan E Hernandez-Avila; Isabelle Romieu; Karen E Peterson; Antonio Aro; Eduardo Palazuelos; Howard Hu
Journal:  Epidemiology       Date:  2003-03       Impact factor: 4.822

Review 8.  Blood lead levels in children aged 24 to 36 months in Vancouver.

Authors:  A Jin; C Hertzman; S H Peck; G Lockitch
Journal:  CMAJ       Date:  1995-04-01       Impact factor: 8.262

9.  Prevalence of excess lead absorption and associated risk factors in children enrolled in a midwestern health maintenance organization.

Authors:  J D Nordin; S J Rolnick; J M Griffin
Journal:  Pediatrics       Date:  1994-02       Impact factor: 7.124

Review 10.  Lead.

Authors:  David C Bellinger
Journal:  Pediatrics       Date:  2004-04       Impact factor: 7.124

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  8 in total

1.  Bone lead measurement.

Authors:  Mark Payne; Lesley Egden; Sepideh Behinaein; David Chettle; Fiona McNeill; Colin Webber
Journal:  Can Fam Physician       Date:  2010-11       Impact factor: 3.275

Review 2. 

Authors:  Patricia Li; Leslie Rourke; Denis Leduc; Stephani Arulthas; Karen Rezk; James Rourke
Journal:  Can Fam Physician       Date:  2019-03       Impact factor: 3.275

Review 3.  Rourke Baby Record 2017: Clinical update for preventive care of children up to 5 years of age.

Authors:  Patricia Li; Leslie Rourke; Denis Leduc; Stephani Arulthas; Karen Rezk; James Rourke
Journal:  Can Fam Physician       Date:  2019-03       Impact factor: 3.275

4.  Getting it right from birth to kindergarten: what's new in the Rourke Baby Record?

Authors:  Leslie Rourke; Denis Leduc; Evelyn Constantin; Sarah Carsley; James Rourke; Patricia Li
Journal:  Can Fam Physician       Date:  2013-04       Impact factor: 3.275

5.  Correlation analysis of the long latency auditory evoked potential N2 and cognitive P3 with the level of lead poisoning in children.

Authors:  Kátia de Freitas Alvarenga; Gabriela Rosito Alvarez Bernardez-Braga; Fernanda Zucki; Josilene Luciene Duarte; Andrea Cintra Lopes; Mariza Ribeiro Feniman
Journal:  Int Arch Otorhinolaryngol       Date:  2013-01

6.  E-Waste Informal Recycling: An Emerging Source of Lead Exposure in South America.

Authors:  Antonio Pascale; Adriana Sosa; Cristina Bares; Alejandra Battocletti; María José Moll; Darío Pose; Amalia Laborde; Hugo González; Gabriella Feola
Journal:  Ann Glob Health       Date:  2016 Jan-Feb       Impact factor: 2.462

7.  Playground lead levels in rubber, soil, sand, and mulch surfaces in Boston.

Authors:  Khaled S Almansour; Nicholas J Arisco; May K Woo; Anna S Young; Gary Adamkiewicz; Jaime E Hart
Journal:  PLoS One       Date:  2019-04-25       Impact factor: 3.240

8.  Reference values of lead in blood and related factors among Korean adolescents: the Korean National Health and Nutrition Examination Survey 2010-2013.

Authors:  Min-Gyu Choi; Mi-Jung Park; Shin-Hye Kim
Journal:  Korean J Pediatr       Date:  2016-03-31
  8 in total

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