| Literature DB >> 20546919 |
Elise Verron1, Ibrahim Khairoun, Jerome Guicheux, Jean-Michel Bouler.
Abstract
A short review is proposed on the existing literature for the research performed in calcium phosphate (CaP) biomaterials used as drug delivery systems. In the first part, a brief update is given on the performance of both CaP ceramics and CaP cements. Second, a review of the research and clinical situation is developed for CaP materials already used as drug delivery systems. Experimental works performed for local delivery are reported. In particular, a description is given of the in vitro and in vivo studies in which these materials are loaded with various proteins and drugs. 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20546919 DOI： 10.1016/j.drudis.2010.05.003
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851