OBJECTIVES: To demonstrate the usefulness of transurethral resection in one piece (TURBO) as an accurate pathological staging tool for bladder tumor. METHODS: Ninety-seven patients with newly diagnosed bladder cancer underwent TURBO that was performed either in an en bloc or in a divisional manner. The histological quality of the resection specimens was evaluated and the pathological stage was assigned on the basis of the depth of invasion, which was histologically determined. RESULTS: Specimens obtained by TURBO were well oriented and their 3-D architecture was maintained. This allowed a histological assessment of the entire specimen. Portions of muscularis propria were identified beneath the tumor base in the specimens of 80 (82%) patients. In only seven (7%) patients, the tumors had a deep resection margin positive for carcinoma and were ambiguously staged as "pT1 or higher" or "pT2 or higher". Thus, definite pathological staging of TURBO specimens was possible in 90 (93%) patients (pTa, 30; pT1, 58; pT2, 2). CONCLUSIONS: An accurate pathological stage can be assigned to the TURBO specimen in most bladder cancer patients.
OBJECTIVES: To demonstrate the usefulness of transurethral resection in one piece (TURBO) as an accurate pathological staging tool for bladder tumor. METHODS: Ninety-seven patients with newly diagnosed bladder cancer underwent TURBO that was performed either in an en bloc or in a divisional manner. The histological quality of the resection specimens was evaluated and the pathological stage was assigned on the basis of the depth of invasion, which was histologically determined. RESULTS: Specimens obtained by TURBO were well oriented and their 3-D architecture was maintained. This allowed a histological assessment of the entire specimen. Portions of muscularis propria were identified beneath the tumor base in the specimens of 80 (82%) patients. In only seven (7%) patients, the tumors had a deep resection margin positive for carcinoma and were ambiguously staged as "pT1 or higher" or "pT2 or higher". Thus, definite pathological staging of TURBO specimens was possible in 90 (93%) patients (pTa, 30; pT1, 58; pT2, 2). CONCLUSIONS: An accurate pathological stage can be assigned to the TURBO specimen in most bladder cancerpatients.
Authors: M W Kramer; M Wolters; I F Abdelkawi; A S Merseburger; U Nagele; A Gross; T Bach; M A Kuczyk; T R W Herrmann Journal: Urologe A Date: 2012-06 Impact factor: 0.639
Authors: Mario W Kramer; Jens J Rassweiler; Jan Klein; Alexey Martov; Nikolay Baykov; Lukas Lusuardi; Günter Janetschek; Rodolfo Hurle; Mathias Wolters; Mahmoud Abbas; Christoph A von Klot; Armin Leitenberger; Markus Riedl; Udo Nagele; Axel S Merseburger; Markus A Kuczyk; Marko Babjuk; Thomas R W Herrmann Journal: World J Urol Date: 2015-04-25 Impact factor: 4.226