OBJECTIVES: To evaluate the risk factors for recurrent falling and mortality in Parkinson's disease (PD) in a prospective study design. MATERIALS AND METHODS: One hundred and twenty-five PD patients were included in the study. Baseline medical data were collected, and patients were clinically tested for mobility and balance. Falls were prospectively recorded for 2 years. Mortality was documented 4 years after the baseline. RESULTS: Seventy-nine patients reported altogether 3125 falls during the follow-up, and 59 patients were classified as recurrent fallers. Altogether 126 fall injuries including six fractures were reported. Eighteen patients had died by the time of the hospital chart review. History of falling (OR 3.02, 95% CI 1.23-7.44) and the Unified Parkinson's Disease Rating Scale activities of daily living score (OR 1.13, 95% CI 1.04-1.22) were independent risk factors for recurrent falling in PD, whereas slow walking speed (OR 16.28, 95% CI 1.85-142.97) was an independent risk factor for mortality in PD. CONCLUSIONS: History of falling and disease severity indicate increased risk of recurrent falls in PD, while patients with slow walking speed may have an increased risk of mortality. Recurrent falling was not associated with increased risk of mortality in PD in this study.
OBJECTIVES: To evaluate the risk factors for recurrent falling and mortality in Parkinson's disease (PD) in a prospective study design. MATERIALS AND METHODS: One hundred and twenty-five PDpatients were included in the study. Baseline medical data were collected, and patients were clinically tested for mobility and balance. Falls were prospectively recorded for 2 years. Mortality was documented 4 years after the baseline. RESULTS: Seventy-nine patients reported altogether 3125 falls during the follow-up, and 59 patients were classified as recurrent fallers. Altogether 126 fall injuries including six fractures were reported. Eighteen patients had died by the time of the hospital chart review. History of falling (OR 3.02, 95% CI 1.23-7.44) and the Unified Parkinson's Disease Rating Scale activities of daily living score (OR 1.13, 95% CI 1.04-1.22) were independent risk factors for recurrent falling in PD, whereas slow walking speed (OR 16.28, 95% CI 1.85-142.97) was an independent risk factor for mortality in PD. CONCLUSIONS: History of falling and disease severity indicate increased risk of recurrent falls in PD, while patients with slow walking speed may have an increased risk of mortality. Recurrent falling was not associated with increased risk of mortality in PD in this study.
Authors: Sotirios A Parashos; Jordan Elm; James T Boyd; Kelvin L Chou; Lin Dai; Zoltan Mari; John C Morgan; Lewis Sudarsky; Catherine L Wielinski Journal: J Parkinsons Dis Date: 2015 Impact factor: 5.568
Authors: Ryan P Duncan; Abigail L Leddy; James T Cavanaugh; Leland E Dibble; Terry D Ellis; Matthew P Ford; K Bo Foreman; Gammon M Earhart Journal: J Parkinsons Dis Date: 2015 Impact factor: 5.568
Authors: Digna de Kam; Jorik Nonnekes; Lars B Oude Nijhuis; Alexander C H Geurts; Bastiaan R Bloem; Vivian Weerdesteyn Journal: J Neurol Date: 2014-09-17 Impact factor: 4.849
Authors: René D Verboket; Laurent M Willems; Nils Mühlenfeld; Nicolas Söhling; Ingo Marzi; Martin Pieper; Esther Paule; Philipp S Reif; Adam Strzelczyk Journal: Eur J Trauma Emerg Surg Date: 2019-10-14 Impact factor: 3.693
Authors: Meg E Morris; Clarissa Martin; Jennifer L McGinley; Frances E Huxham; Hylton B Menz; Nicholas F Taylor; Mary Danoudis; Jennifer J Watts; Sze-Ee Soh; Andrew H Evans; Malcolm Horne; Peter Kempster Journal: BMC Neurol Date: 2012-07-16 Impact factor: 2.474
Authors: Nikki Delgado; Daniella Iglesias Hernandez; Keith Radler; Edward D Huey; Stephanie Cosentino; Elan Louis Journal: J Neurol Sci Date: 2021-07-02 Impact factor: 4.553